# FedSKD: Aggregation-free Model-heterogeneous Federated Learning via Multi-dimensional Similarity Knowledge Distillation for Medical Image Classification

arXiv: https://arxiv.org/abs/2503.18981 · HTML: https://mlsanity.com/paper/2503.18981/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Federated, robust and private distillation, one of 12 directions in Knowledge distillation.
- Builds on 50 of its 79 references that are in the map.
- First posted on arXiv 23 Mar 2025.

## Placed in

- Knowledge distillation / [Federated, robust and private distillation](https://mlsanity.com/distill/federated-robust-and-private-distillation/)

## Builds on (most cited first, 30 of 50)

- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Advances and Open Problems in Federated Learning](https://mlsanity.com/paper/1912.04977/) (2019)
- [Federated Optimization in Heterogeneous Networks](https://mlsanity.com/paper/1812.06127/) (2018)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [Paying More Attention to Attention: Improving the Performance of Convolutional Neural Networks via Attention Transfer](https://mlsanity.com/paper/1612.03928/) (2016)
- [Ensemble Distillation for Robust Model Fusion in Federated Learning](https://mlsanity.com/paper/2006.07242/) (2020)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [FedBN: Federated Learning on Non-IID Features via Local Batch Normalization](https://mlsanity.com/paper/2102.07623/) (2021)
- [FedMD: Heterogenous Federated Learning via Model Distillation](https://mlsanity.com/paper/1910.03581/) (2019)
- [Agnostic Federated Learning](https://mlsanity.com/paper/1902.00146/) (2019)
- [Fair Resource Allocation in Federated Learning](https://mlsanity.com/paper/1905.10497/) (2019)
- [Data-Free Knowledge Distillation for Heterogeneous Federated Learning](https://mlsanity.com/paper/2105.10056/) (2021)
- [FedKD: Communication Efficient Federated Learning via Knowledge Distillation](https://mlsanity.com/paper/2108.13323/) (2021)
- [Federated Continual Learning with Weighted Inter-client Transfer](https://mlsanity.com/paper/2003.03196/) (2020)
- [Distillation-Based Semi-Supervised Federated Learning for Communication-Efficient Collaborative Training with Non-IID Private Data](https://mlsanity.com/paper/2008.06180/) (2020)
- [Multi-site fMRI Analysis Using Privacy-preserving Federated Learning and Domain Adaptation: ABIDE Results](https://mlsanity.com/paper/2001.05647/) (2020)
- [BrainTorrent: A Peer-to-Peer Environment for Decentralized Federated Learning](https://mlsanity.com/paper/1905.06731/) (2019)
- [Cronus: Robust and Heterogeneous Collaborative Learning with Black-Box Knowledge Transfer](https://mlsanity.com/paper/1912.11279/) (2019)
- [Decentralized Federated Learning: A Survey and Perspective](https://mlsanity.com/paper/2306.01603/) (2023)
- [Peer-to-peer Federated Learning on Graphs](https://mlsanity.com/paper/1901.11173/) (2019)
- [Heterogeneous Ensemble Knowledge Transfer for Training Large Models in Federated Learning](https://mlsanity.com/paper/2204.12703/) (2022)
- [Multi-institutional Collaborations for Improving Deep Learning-based Magnetic Resonance Image Reconstruction Using Federated Learning](https://mlsanity.com/paper/2103.02148/) (2021)
- [Federated Learning for Medical Image Analysis: A Survey](https://mlsanity.com/paper/2306.05980/) (2023)
- [FedGEMS: Federated Learning of Larger Server Models via Selective Knowledge Fusion](https://mlsanity.com/paper/2110.11027/) (2021)
- [FairMedFM: Fairness Benchmarking for Medical Imaging Foundation Models](https://mlsanity.com/paper/2407.00983/) (2024)
- [Label-Efficient Self-Supervised Federated Learning for Tackling Data Heterogeneity in Medical Imaging](https://mlsanity.com/paper/2205.08576/) (2022)
- [Non-IID data and Continual Learning processes in Federated Learning: A long road ahead](https://mlsanity.com/paper/2111.13394/) (2021)
- [Decentralized Federated Learning via SGD over Wireless D2D Networks](https://mlsanity.com/paper/2002.12507/) (2020)
- [Towards Model Agnostic Federated Learning Using Knowledge Distillation](https://mlsanity.com/paper/2110.15210/) (2021)
- [Towards Personalized Federated Learning via Heterogeneous Model Reassembly](https://mlsanity.com/paper/2308.08643/) (2023)

## Built on by (most cited first, 1 of 1)

- [FedTopo: Relation-Level Topology Sharing for Model-Heterogeneous Federated Learning](https://mlsanity.com/paper/2607.26801/) (2026)

## Abstract (arXiv)

Federated learning (FL) enables privacy-preserving collaborative model training without direct data sharing. Model-heterogeneous FL (MHFL) extends this paradigm by allowing clients to train personalized models with heterogeneous architectures tailored to their computational resources and application-specific needs. However, existing MHFL methods predominantly rely on centralized aggregation, which introduces scalability and efficiency bottlenecks, or impose restrictions requiring partially identical model architectures across clients. While peer-to-peer (P2P) FL removes server dependence, it suffers from model drift and knowledge dilution, limiting its effectiveness in heterogeneous settings. To address these challenges, we propose FedSKD, a novel MHFL framework that facilitates direct knowledge exchange through round-robin model circulation, eliminating the need for centralized aggregation while allowing fully heterogeneous model architectures across clients. FedSKD's key innovation lies in multi-dimensional similarity knowledge distillation, which enables bidirectional cross-client knowledge transfer at batch, pixel/voxel, and region levels for heterogeneous models in FL. This approach mitigates catastrophic forgetting and model drift through progressive reinforcement and distribution alignment while preserving model heterogeneity. Extensive evaluations on fMRI-based autism spectrum disorder diagnosis and skin lesion classification demonstrate that FedSKD outperforms state-of-the-art heterogeneous and homogeneous FL baselines, achieving superior personalization (client-specific accuracy) and generalization (cross-institutional adaptability). These findings underscore FedSKD's potential as a scalable and robust solution for real-world medical federated learning applications.
