# SciHorizon: Benchmarking AI-for-Science Readiness from Scientific Data to Large Language Models

arXiv: https://arxiv.org/abs/2503.13503 · HTML: https://mlsanity.com/paper/2503.13503/

## Key facts

- Cited by 15 papers in the map (data through 14 Oct 2026).
- Builds on 41 of its 117 references that are in the map.
- First posted on arXiv 12 Mar 2025.

## Builds on (most cited first, 30 of 41)

- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Training Verifiers to Solve Math Word Problems](https://mlsanity.com/paper/2110.14168/) (2021)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [GPQA: A Graduate-Level Google-Proof Q&A Benchmark](https://mlsanity.com/paper/2311.12022/) (2023)
- [Beyond the Imitation Game: Quantifying and extrapolating the capabilities of language models](https://mlsanity.com/paper/2206.04615/) (2022)
- [Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answering](https://mlsanity.com/paper/2209.09513/) (2022)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [MathVista: Evaluating Mathematical Reasoning of Foundation Models in Visual Contexts](https://mlsanity.com/paper/2310.02255/) (2023)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [A Survey on Evaluation of Large Language Models](https://mlsanity.com/paper/2307.03109/) (2023)
- [AGIEval: A Human-Centric Benchmark for Evaluating Foundation Models](https://mlsanity.com/paper/2304.06364/) (2023)
- [C-Eval: A Multi-Level Multi-Discipline Chinese Evaluation Suite for Foundation Models](https://mlsanity.com/paper/2305.08322/) (2023)
- [MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classification](https://mlsanity.com/paper/2110.14795/) (2021)
- [MathQA: Towards Interpretable Math Word Problem Solving with Operation-Based Formalisms](https://mlsanity.com/paper/1905.13319/) (2019)
- [Program Induction by Rationale Generation : Learning to Solve and Explain Algebraic Word Problems](https://mlsanity.com/paper/1705.04146/) (2017)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [CMMLU: Measuring massive multitask language understanding in Chinese](https://mlsanity.com/paper/2306.09212/) (2023)
- [A Survey on Large Language Models for Recommendation](https://mlsanity.com/paper/2305.19860/) (2023)
- [Mathematical Capabilities of ChatGPT](https://mlsanity.com/paper/2301.13867/) (2023)
- [SciBench: Evaluating College-Level Scientific Problem-Solving Abilities of Large Language Models](https://mlsanity.com/paper/2307.10635/) (2023)
- [TheoremQA: A Theorem-driven Question Answering dataset](https://mlsanity.com/paper/2305.12524/) (2023)
- [What can Large Language Models do in chemistry? A comprehensive benchmark on eight tasks](https://mlsanity.com/paper/2305.18365/) (2023)
- [The Privacy Onion Effect: Memorization is Relative](https://mlsanity.com/paper/2206.10469/) (2022)
- [GEO-Bench: Toward Foundation Models for Earth Monitoring](https://mlsanity.com/paper/2306.03831/) (2023)
- [CMB: A Comprehensive Medical Benchmark in Chinese](https://mlsanity.com/paper/2308.08833/) (2023)
- [SciEval: A Multi-Level Large Language Model Evaluation Benchmark for Scientific Research](https://mlsanity.com/paper/2308.13149/) (2023)
- [MathBench: Evaluating the Theory and Application Proficiency of LLMs with a Hierarchical Mathematics Benchmark](https://mlsanity.com/paper/2405.12209/) (2024)
- [Have LLMs Advanced Enough? A Challenging Problem Solving Benchmark For Large Language Models](https://mlsanity.com/paper/2305.15074/) (2023)
- [Hypothesis Generation with Large Language Models](https://mlsanity.com/paper/2404.04326/) (2024)
- [FELM: Benchmarking Factuality Evaluation of Large Language Models](https://mlsanity.com/paper/2310.00741/) (2023)

## Built on by (most cited first, 15 of 15)

- [A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers](https://mlsanity.com/paper/2508.21148/) (2025)
- [MobilityBench: A Benchmark for Evaluating Route-Planning Agents in Real-World Mobility Scenarios](https://mlsanity.com/paper/2602.22638/) (2026)
- [FastFT: Accelerating Reinforced Feature Transformation via Advanced Exploration Strategies](https://mlsanity.com/paper/2503.20394/) (2025)
- [SciRerankBench: Benchmarking Rerankers Towards Scientific Retrieval-Augmented Generated LLMs](https://mlsanity.com/paper/2508.08742/) (2025)
- [VASP Agent: An Agentic Framework for Autonomous First-principles Calculations](https://mlsanity.com/paper/2512.19458/) (2025)
- [SciDataCopilot: An Agentic Data Preparation Framework for AGI-driven Scientific Discovery](https://mlsanity.com/paper/2602.09132/) (2026)
- [EvoDS: Self-Evolving Autonomous Data Science Agent with Skill Learning and Context Management](https://mlsanity.com/paper/2606.03841/) (2026)
- [Knowledge-Driven Agentic Scientific Corpus Distillation Framework for Biomedical Large Language Models Training](https://mlsanity.com/paper/2504.19565/) (2025)
- [Active Inference AI Systems for Scientific Discovery](https://mlsanity.com/paper/2506.21329/) (2025)
- [SciHorizon-GENE: Benchmarking LLM for Life Sciences Inference from Gene Knowledge to Functional Understanding](https://mlsanity.com/paper/2601.12805/) (2026)
- [CEDAR: Controlled and Event-Driven Demand Forecasting via Residual Decomposition](https://mlsanity.com/paper/2608.25871/) (2026)
- [From Entity Reliability to Clean Feedback: An Entity-Aware Denoising Framework Beyond Interaction-Level Signals](https://mlsanity.com/paper/2508.10851/) (2025)
- [SciHorizon-DataEVA: An Agentic System for AI-Readiness Evaluation of Heterogeneous Scientific Data](https://mlsanity.com/paper/2604.26645/) (2026)
- [IPO-Mine: A Toolkit and Dataset for Section-Structured Analysis of Long, Multimodal IPO Documents](https://mlsanity.com/paper/2605.28714/) (2026)
- [Building AI-Ready Data Systems for Space Life Sciences, Aerospace Medicine, and Deep Space Exploration](https://mlsanity.com/paper/2606.28856/) (2026)

## Abstract (arXiv)

In recent years, the rapid advancement of Artificial Intelligence (AI) technologies, particularly Large Language Models (LLMs), has revolutionized the paradigm of scientific discovery, establishing AI-for-Science (AI4Science) as a dynamic and evolving field. However, there is still a lack of an effective framework for the overall assessment of AI4Science, particularly from a holistic perspective on data quality and model capability. Therefore, in this study, we propose SciHorizon, a comprehensive assessment framework designed to benchmark the readiness of AI4Science from both scientific data and LLM perspectives. First, we introduce a generalizable framework for assessing AI-ready scientific data, encompassing four key dimensions: Quality, FAIRness, Explainability, and Compliance-which are subdivided into 15 sub-dimensions. Drawing on data resource papers published between 2018 and 2023 in peer-reviewed journals, we present recommendation lists of AI-ready datasets for Earth, Life, and Materials Sciences, making a novel and original contribution to the field. Concurrently, to assess the capabilities of LLMs across multiple scientific disciplines, we establish 16 assessment dimensions based on five core indicators Knowledge, Understanding, Reasoning, Multimodality, and Values spanning Mathematics, Physics, Chemistry, Life Sciences, and Earth and Space Sciences. Using the developed benchmark datasets, we have conducted a comprehensive evaluation of over 50 representative open-source and closed source LLMs. All the results are publicly available and can be accessed online at www.scihorizon.cn/en.