# Synthetic Lung X-ray Generation through Cross-Attention and Affinity Transformation

arXiv: https://arxiv.org/abs/2503.07209 · HTML: https://mlsanity.com/paper/2503.07209/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 12 of its 21 references that are in the map.
- First posted on arXiv 10 Mar 2025.

## Builds on (most cited first, 12 of 12)

- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [Large Scale GAN Training for High Fidelity Natural Image Synthesis](https://mlsanity.com/paper/1809.11096/) (2018)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [Density estimation using Real NVP](https://mlsanity.com/paper/1605.08803/) (2016)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation](https://mlsanity.com/paper/1511.00561/) (2015)
- [Medical Image Segmentation Using Deep Learning: A Survey](https://mlsanity.com/paper/2009.13120/) (2020)
- [DiffuMask: Synthesizing Images with Pixel-level Annotations for Semantic Segmentation Using Diffusion Models](https://mlsanity.com/paper/2303.11681/) (2023)
- [Efficient Interactive Annotation of Segmentation Datasets with Polygon-RNN++](https://mlsanity.com/paper/1803.09693/) (2018)
- [Zero-shot spatial layout conditioning for text-to-image diffusion models](https://mlsanity.com/paper/2306.13754/) (2023)

## Built on by (most cited first, 3 of 3)

- [GDGS: 3D Gaussian Splatting Via Geometry-Guided Initialization And Dynamic Density Control](https://mlsanity.com/paper/2507.00363/) (2025)
- [A Global-Local Cross-Attention Network for Ultra-high Resolution Remote Sensing Image Semantic Segmentation](https://mlsanity.com/paper/2506.19406/) (2025)
- [MAViE: A Multi-scale Adaptive Vision Encoder for Fine-grained Visual Perception and Efficient Multimodal Reasoning](https://mlsanity.com/paper/2607.24424/) (2026)

## Abstract (arXiv)

Collecting and annotating medical images is a time-consuming and resource-intensive task. However, generating synthetic data through models such as Diffusion offers a cost-effective alternative. This paper introduces a new method for the automatic generation of accurate semantic masks from synthetic lung X-ray images based on a stable diffusion model trained on text-image pairs. This method uses cross-attention mapping between text and image to extend text-driven image synthesis to semantic mask generation. It employs text-guided cross-attention information to identify specific areas in an image and combines this with innovative techniques to produce high-resolution, class-differentiated pixel masks. This approach significantly reduces the costs associated with data collection and annotation. The experimental results demonstrate that segmentation models trained on synthetic data generated using the method are comparable to, and in some cases even better than, models trained on real datasets. This shows the effectiveness of the method and its potential to revolutionize medical image analysis.