# Q-PART: Quasi-Periodic Adaptive Regression with Test-time Training for Pediatric Left Ventricular Ejection Fraction Regression

arXiv: https://arxiv.org/abs/2503.04131 · HTML: https://mlsanity.com/paper/2503.04131/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 18 of its 41 references that are in the map.
- First posted on arXiv 6 Mar 2025.

## Builds on (most cited first, 18 of 18)

- [A Closer Look at Spatiotemporal Convolutions for Action Recognition](https://mlsanity.com/paper/1711.11248/) (2017)
- [Neural Controlled Differential Equations for Irregular Time Series](https://mlsanity.com/paper/2005.08926/) (2020)
- [Efficient Test-Time Model Adaptation without Forgetting](https://mlsanity.com/paper/2204.02610/) (2022)
- [Improving robustness against common corruptions by covariate shift adaptation](https://mlsanity.com/paper/2006.16971/) (2020)
- [MEMO: Test Time Robustness via Adaptation and Augmentation](https://mlsanity.com/paper/2110.09506/) (2021)
- [A Comprehensive Survey on Test-Time Adaptation under Distribution Shifts](https://mlsanity.com/paper/2303.15361/) (2023)
- [CLIP-Driven Universal Model for Organ Segmentation and Tumor Detection](https://mlsanity.com/paper/2301.00785/) (2023)
- [Test-Time Training with Masked Autoencoders](https://mlsanity.com/paper/2209.07522/) (2022)
- [DELTA: degradation-free fully test-time adaptation](https://mlsanity.com/paper/2301.13018/) (2023)
- [RDumb: A simple approach that questions our progress in continual test-time adaptation](https://mlsanity.com/paper/2306.05401/) (2023)
- [Domain Generalization via Inference-time Label-Preserving Target Projections](https://mlsanity.com/paper/2103.01134/) (2021)
- [TTTFlow: Unsupervised Test-Time Training with Normalizing Flow](https://mlsanity.com/paper/2210.11389/) (2022)
- [ClusT3: Information Invariant Test-Time Training](https://mlsanity.com/paper/2310.12345/) (2023)
- [Online Domain Adaptation for Semantic Segmentation in Ever-Changing Conditions](https://mlsanity.com/paper/2207.10667/) (2022)
- [EchoCoTr: Estimation of the Left Ventricular Ejection Fraction from Spatiotemporal Echocardiography](https://mlsanity.com/paper/2209.04242/) (2022)
- [Cyclical Self-Supervision for Semi-Supervised Ejection Fraction Prediction from Echocardiogram Videos](https://mlsanity.com/paper/2210.11291/) (2022)
- [CoReEcho: Continuous Representation Learning for 2D+time Echocardiography Analysis](https://mlsanity.com/paper/2403.10164/) (2024)
- [REALM: Robust Entropy Adaptive Loss Minimization for Improved Single-Sample Test-Time Adaptation](https://mlsanity.com/paper/2309.03964/) (2023)

## Built on by (most cited first, 1 of 1)

- [EchoAgent: Towards Reliable Echocardiography Interpretation with "Eyes","Hands" and "Minds"](https://mlsanity.com/paper/2604.05541/) (2026)

## Abstract (arXiv)

In this work, we address the challenge of adaptive pediatric Left Ventricular Ejection Fraction (LVEF) assessment. While Test-time Training (TTT) approaches show promise for this task, they suffer from two significant limitations. Existing TTT works are primarily designed for classification tasks rather than continuous value regression, and they lack mechanisms to handle the quasi-periodic nature of cardiac signals. To tackle these issues, we propose a novel Quasi-Periodic Adaptive Regression with Test-time Training (Q-PART) framework. In the training stage, the proposed Quasi-Period Network decomposes the echocardiogram into periodic and aperiodic components within latent space by combining parameterized helix trajectories with Neural Controlled Differential Equations. During inference, our framework further employs a variance minimization strategy across image augmentations that simulate common quality issues in echocardiogram acquisition, along with differential adaptation rates for periodic and aperiodic components. Theoretical analysis is provided to demonstrate that our variance minimization objective effectively bounds the regression error under mild conditions. Furthermore, extensive experiments across three pediatric age groups demonstrate that Q-PART not only significantly outperforms existing approaches in pediatric LVEF prediction, but also exhibits strong clinical screening capability with high mAUROC scores (up to 0.9747) and maintains gender-fair performance across all metrics, validating its robustness and practical utility in pediatric echocardiography analysis.
