# Rapid Bone Scintigraphy Enhancement via Semantic Prior Distillation from Segment Anything Model

arXiv: https://arxiv.org/abs/2503.02321 · HTML: https://mlsanity.com/paper/2503.02321/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 28 of its 53 references that are in the map.
- First posted on arXiv 4 Mar 2025.

## Builds on (most cited first, 28 of 28)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [SwinIR: Image Restoration Using Swin Transformer](https://mlsanity.com/paper/2108.10257/) (2021)
- [Restormer: Efficient Transformer for High-Resolution Image Restoration](https://mlsanity.com/paper/2111.09881/) (2021)
- [Enhanced Deep Residual Networks for Single Image Super-Resolution](https://mlsanity.com/paper/1707.02921/) (2017)
- [Beyond a Gaussian Denoiser: Residual Learning of Deep CNN for Image Denoising](https://mlsanity.com/paper/1608.03981/) (2016)
- [Image Super-Resolution Using Deep Convolutional Networks](https://mlsanity.com/paper/1501.00092/) (2014)
- [Simple Baselines for Image Restoration](https://mlsanity.com/paper/2204.04676/) (2022)
- [Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.12620/) (2023)
- [Customized Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.13785/) (2023)
- [Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)](https://mlsanity.com/paper/1702.00288/) (2017)
- [Human-Aware Motion Deblurring](https://mlsanity.com/paper/2001.06816/) (2020)
- [Large AI Models in Health Informatics: Applications, Challenges, and the Future](https://mlsanity.com/paper/2303.11568/) (2023)
- [How to Efficiently Adapt Large Segmentation Model(SAM) to Medical Images](https://mlsanity.com/paper/2306.13731/) (2023)
- [An Arbitrary Scale Super-Resolution Approach for 3D MR Images via Implicit Neural Representation](https://mlsanity.com/paper/2110.14476/) (2021)
- [Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decoding](https://mlsanity.com/paper/2403.18271/) (2024)
- [TransCT: Dual-path Transformer for Low Dose Computed Tomography](https://mlsanity.com/paper/2103.00634/) (2021)
- [All-In-One Medical Image Restoration via Task-Adaptive Routing](https://mlsanity.com/paper/2405.19769/) (2024)
- [Distilling Semantic Priors from SAM to Efficient Image Restoration Models](https://mlsanity.com/paper/2403.16368/) (2024)
- [An Annotation-free Restoration Network for Cataractous Fundus Images](https://mlsanity.com/paper/2203.07737/) (2022)
- [Cross Prompting Consistency with Segment Anything Model for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2407.05416/) (2024)
- [Let Segment Anything Help Image Dehaze](https://mlsanity.com/paper/2306.15870/) (2023)
- [SAM-Deblur: Let Segment Anything Boost Image Deblurring](https://mlsanity.com/paper/2309.02270/) (2023)
- [A Dive into SAM Prior in Image Restoration](https://mlsanity.com/paper/2305.13620/) (2023)
- [Sam-Guided Enhanced Fine-Grained Encoding with Mixed Semantic Learning for Medical Image Captioning](https://mlsanity.com/paper/2311.01004/) (2023)
- [Restore Anything Pipeline: Segment Anything Meets Image Restoration](https://mlsanity.com/paper/2305.13093/) (2023)
- [GlanceSeg: Real-time microaneurysm lesion segmentation with gaze-map-guided foundation model for early detection of diabetic retinopathy](https://mlsanity.com/paper/2311.08075/) (2023)

## Abstract (arXiv)

Rapid bone scintigraphy is crucial for diagnosing skeletal disorders and detecting tumor metastases in children, as it shortens scan duration and reduces discomfort. However, accelerated acquisition often degrades image quality, impairing the visibility of fine anatomical details and potentially compromising diagnosis. To overcome this limitation, we introduce the first application of SAM-based semantic priors for medical image restoration, utilizing the Segment Anything Model (SAM) to enhance pediatric rapid bone scintigraphy. Our approach employs two cascaded networks, fIR1 and fIR2, supported by three specialized modules: a Semantic Prior Integration (SPI) module, a Semantic Knowledge Distillation (SKD) module, and a Semantic Consistency Module (SCM). The SPI and SKD modules inject domain-specific semantic cues from a fine-tuned SAM, while the SCM preserves coherent semantic feature representations across both cascaded stages. Moreover, we present RBS, a novel Rapid Bone Scintigraphy dataset comprising paired standard (20 cm/min) and rapid (40 cm/min) scans from 137 pediatric patients aged 0.5 - 16 years, making it the first dataset tailored for pediatric rapid bone scintigraphy restoration. Extensive experiments on both a public endoscopic dataset and our RBS dataset demonstrate that our method consistently surpasses existing techniques in PSNR, SSIM, FID, and LPIPS metrics.