# TractCloud-FOV: Deep Learning-based Robust Tractography Parcellation in Diffusion MRI with Incomplete Field of View

arXiv: https://arxiv.org/abs/2502.20637 · HTML: https://mlsanity.com/paper/2502.20637/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 42 references that are in the map.
- First posted on arXiv 28 Feb 2025.

## Builds on (most cited first, 17 of 17)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [PointNet: Deep Learning on Point Sets for 3D Classification and Segmentation](https://mlsanity.com/paper/1612.00593/) (2016)
- [Dynamic Graph CNN for Learning on Point Clouds](https://mlsanity.com/paper/1801.07829/) (2018)
- [TractSeg - Fast and accurate white matter tract segmentation](https://mlsanity.com/paper/1805.07103/) (2018)
- [Robust machine learning segmentation for large-scale analysis of heterogeneous clinical brain MRI datasets](https://mlsanity.com/paper/2209.02032/) (2022)
- [Superficial White Matter Analysis: An Efficient Point-cloud-based Deep Learning Framework with Supervised Contrastive Learning for Consistent Tractography Parcellation across Populations and dMRI Acquisitions](https://mlsanity.com/paper/2207.08975/) (2022)
- [Deep Fiber Clustering: Anatomically Informed Unsupervised Deep Learning for Fast and Effective White Matter Parcellation](https://mlsanity.com/paper/2107.04938/) (2021)
- [Deep fiber clustering: Anatomically informed fiber clustering with self-supervised deep learning for fast and effective tractography parcellation](https://mlsanity.com/paper/2205.00627/) (2022)
- [TractGeoNet: A geometric deep learning framework for pointwise analysis of tract microstructure to predict language assessment performance](https://mlsanity.com/paper/2307.03982/) (2023)
- [White Matter Tracts are Point Clouds: Neuropsychological Score Prediction and Critical Region Localization via Geometric Deep Learning](https://mlsanity.com/paper/2207.02402/) (2022)
- [TractoSCR: A Novel Supervised Contrastive Regression Framework for Prediction of Neurocognitive Measures Using Multi-Site Harmonized Diffusion MRI Tractography](https://mlsanity.com/paper/2210.07411/) (2022)
- [Reconstructing the somatotopic organization of the corticospinal tract remains a challenge for modern tractography methods](https://mlsanity.com/paper/2306.05623/) (2023)
- [TractGraphFormer: Anatomically Informed Hybrid Graph CNN-Transformer Network for Interpretable Sex and Age Prediction from Diffusion MRI Tractography](https://mlsanity.com/paper/2407.08883/) (2024)
- [Field-of-View Extension for Brain Diffusion MRI via Deep Generative Models](https://mlsanity.com/paper/2405.03652/) (2024)
- [Multi-Modality Conditioned Variational U-Net for Field-of-View Extension in Brain Diffusion MRI](https://mlsanity.com/paper/2409.13846/) (2024)
- [MICCAI-CDMRI 2023 QuantConn Challenge Findings on Achieving Robust Quantitative Connectivity through Harmonized Preprocessing of Diffusion MRI](https://mlsanity.com/paper/2411.09618/) (2024)

## Built on by (most cited first, 3 of 3)

- [A Multimodal Deep Learning Approach for White Matter Shape Prediction in Diffusion MRI Tractography](https://mlsanity.com/paper/2504.18400/) (2025)
- [FiberGeoText: A Vision-Language Model for Population- Level Organization of Superficial White Matter](https://mlsanity.com/paper/2610.02755/) (2026)
- [Generalizable field of view extension for diffusion MRI via conditional flow matching](https://mlsanity.com/paper/2610.17401/) (2026)

## Abstract (arXiv)

Tractography parcellation classifies streamlines reconstructed from diffusion MRI into anatomically defined fiber tracts for clinical and research applications. However, clinical scans often have incomplete fields of view (FOV) where brain regions are partially imaged, leading to partial or truncated fiber tracts. To address this challenge, we introduce TractCloud-FOV, a deep learning framework that robustly parcellates tractography under conditions of incomplete FOV. We propose a novel training strategy, FOV-Cut Augmentation (FOV-CA), in which we synthetically cut tractograms to simulate a spectrum of real-world inferior FOV cutoff scenarios. This data augmentation approach enriches the training set with realistic truncated streamlines, enabling the model to achieve superior generalization. We evaluate the proposed TractCloud-FOV on both synthetically cut tractography and two real-life datasets with incomplete FOV. TractCloud-FOV significantly outperforms several state-of-the-art methods on all testing datasets in terms of streamline classification accuracy, generalization ability, tract anatomical depiction, and computational efficiency. Overall, TractCloud-FOV achieves efficient and consistent tractography parcellation in diffusion MRI with incomplete FOV.