# Liver Cirrhosis Stage Estimation from MRI with Deep Learning

arXiv: https://arxiv.org/abs/2502.18225 · HTML: https://mlsanity.com/paper/2502.18225/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 31 references that are in the map.
- First posted on arXiv 23 Feb 2025.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Searching for MobileNetV3](https://mlsanity.com/paper/1905.02244/) (2019)
- [Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Model](https://mlsanity.com/paper/2401.09417/) (2024)
- [PVT v2: Improved Baselines with Pyramid Vision Transformer](https://mlsanity.com/paper/2106.13797/) (2021)
- [MambaVision: A Hybrid Mamba-Transformer Vision Backbone](https://mlsanity.com/paper/2407.08083/) (2024)
- [MedMamba: Vision Mamba for Medical Image Classification](https://mlsanity.com/paper/2403.03849/) (2024)
- [Large Scale MRI Collection and Segmentation of Cirrhotic Liver](https://mlsanity.com/paper/2410.16296/) (2024)

## Built on by (most cited first, 1 of 1)

- [CirrGuide: A Deep Cascaded Framework for Liver Cirrhosis Segmentation and Severity Classification from T2-Weighted MRI](https://mlsanity.com/paper/2609.14010/) (2026)

## Abstract (arXiv)

We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early diagnosis is vital to prevent complications such as decompensation and cancer, which significantly decreases life expectancy. However, diagnosing cirrhosis in its early stages is challenging, and patients often present with life-threatening complications. Our approach integrates multi-scale feature learning with sequence-specific attention mechanisms to capture subtle tissue variations across cirrhosis progression stages. Using CirrMRI600+, a large-scale publicly available dataset of 628 high-resolution MRI scans from 339 patients, we demonstrate state-of-the-art performance in three-stage cirrhosis classification. Our best model achieves 72.8% accuracy on T1W and 63.8% on T2W sequences, significantly outperforming traditional radiomics-based approaches. Through extensive ablation studies, we show that our architecture effectively learns stage-specific imaging biomarkers. We establish new benchmarks for automated cirrhosis staging and provide insights for developing clinically applicable deep learning systems. The source code will be available at https://github.com/JunZengz/CirrhosisStage.