# Enhancing LLMs for Identifying and Prioritizing Important Medical Jargons from Electronic Health Record Notes Utilizing Data Augmentation: A Comparative Study

arXiv: https://arxiv.org/abs/2502.16022 · HTML: https://mlsanity.com/paper/2502.16022/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 50 of its 120 references that are in the map.
- First posted on arXiv 22 Feb 2025.

## Builds on (most cited first, 30 of 50)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learning](https://mlsanity.com/paper/2501.12948/) (2025)
- [Finetuned Language Models Are Zero-Shot Learners](https://mlsanity.com/paper/2109.01652/) (2021)
- [Mistral 7B](https://mlsanity.com/paper/2310.06825/) (2023)
- [HuggingFace's Transformers: State-of-the-art Natural Language Processing](https://mlsanity.com/paper/1910.03771/) (2019)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [What Makes Good In-Context Examples for GPT-3?](https://mlsanity.com/paper/2101.06804/) (2021)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [EDA: Easy Data Augmentation Techniques for Boosting Performance on Text Classification Tasks](https://mlsanity.com/paper/1901.11196/) (2019)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [A Comprehensive Capability Analysis of GPT-3 and GPT-3.5 Series Models](https://mlsanity.com/paper/2303.10420/) (2023)
- [ScispaCy: Fast and Robust Models for Biomedical Natural Language Processing](https://mlsanity.com/paper/1902.07669/) (2019)
- [Does Synthetic Data Generation of LLMs Help Clinical Text Mining?](https://mlsanity.com/paper/2303.04360/) (2023)
- [Opportunities and Challenges for ChatGPT and Large Language Models in Biomedicine and Health](https://mlsanity.com/paper/2306.10070/) (2023)
- [Towards Accurate Differential Diagnosis with Large Language Models](https://mlsanity.com/paper/2312.00164/) (2023)
- [An Empirical Survey of Data Augmentation for Limited Data Learning in NLP](https://mlsanity.com/paper/2106.07499/) (2021)
- [Advancing Multimodal Medical Capabilities of Gemini](https://mlsanity.com/paper/2405.03162/) (2024)
- [Thinking about GPT-3 In-Context Learning for Biomedical IE? Think Again](https://mlsanity.com/paper/2203.08410/) (2022)
- [Towards Conversational Diagnostic AI](https://mlsanity.com/paper/2401.05654/) (2024)
- [Launching into clinical space with medspaCy: a new clinical text processing toolkit in Python](https://mlsanity.com/paper/2106.07799/) (2021)

## Abstract (arXiv)

OpenNotes gives patients access to their EHR notes, but dense medical jargon limits comprehension. We evaluate closed-source and open-source LLMs for extracting and prioritizing the jargon terms most relevant to individual patients, using 90 expert-annotated EHR notes. We test combinations of general vs. structured prompts, zero-shot vs. few-shot prompting, fine-tuning, and GPT-4o-based data augmentation, the last paired with a ranking technique to refine training in low-resource settings. To assess the effect of dataset size, we fine-tune on augmented datasets scaled from 10 to 9,995 examples. All settings are evaluated with 10-fold cross-validation, reporting F1 and Mean Reciprocal Rank (MRR) under two string-matching criteria (relaxed matching and Jaccard Index), followed by an error analysis of model outputs. Open-source models performed best when fine-tuned on the gold-standard dataset: under Jaccard-based matching, DeepSeek 8B achieved the top F1 (0.431, SD 0.046) and BioMistral 7B the top MRR (0.577, SD 0.109). Under relaxed matching, however, open-source models did not match closed-source performance even with augmentation or fine-tuning. Few-shot prompting offered no advantage over zero-shot in vanilla models; prompting style substantially affected results; fine-tuning on a small gold-standard set improved performance; and data augmentation matched or exceeded fine-tuning, though its benefit depended heavily on augmented-data quality. These findings show that prompting strategy, fine-tuning, and data augmentation each meaningfully improve LLM performance on patient-centered jargon extraction in low-resource clinical settings.
