# MindLLM: A Subject-Agnostic and Versatile Model for fMRI-to-Text Decoding

arXiv: https://arxiv.org/abs/2502.15786 · HTML: https://mlsanity.com/paper/2502.15786/

## Key facts

- Cited by 14 papers in the map (data through 14 Oct 2026).
- Builds on 59 of its 97 references that are in the map.
- First posted on arXiv 18 Feb 2025.

## Builds on (most cited first, 30 of 59)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Judging LLM-as-a-Judge with MT-Bench and Chatbot Arena](https://mlsanity.com/paper/2306.05685/) (2023)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Models](https://mlsanity.com/paper/2301.12597/) (2023)
- [Flamingo: a Visual Language Model for Few-Shot Learning](https://mlsanity.com/paper/2204.14198/) (2022)
- [Deformable DETR: Deformable Transformers for End-to-End Object Detection](https://mlsanity.com/paper/2010.04159/) (2020)
- [Domain-Adversarial Training of Neural Networks](https://mlsanity.com/paper/1505.07818/) (2015)
- [Visual Genome: Connecting Language and Vision Using Crowdsourced Dense Image Annotations](https://mlsanity.com/paper/1602.07332/) (2016)
- [Making the V in VQA Matter: Elevating the Role of Image Understanding in Visual Question Answering](https://mlsanity.com/paper/1612.00837/) (2016)
- [VQA: Visual Question Answering](https://mlsanity.com/paper/1505.00468/) (2015)
- [Fourier Features Let Networks Learn High Frequency Functions in Low Dimensional Domains](https://mlsanity.com/paper/2006.10739/) (2020)
- [Unsupervised Domain Adaptation by Backpropagation](https://mlsanity.com/paper/1409.7495/) (2014)
- [Video-LLaMA: An Instruction-tuned Audio-Visual Language Model for Video Understanding](https://mlsanity.com/paper/2306.02858/) (2023)
- [Microsoft COCO Captions: Data Collection and Evaluation Server](https://mlsanity.com/paper/1504.00325/) (2015)
- [MLP-Mixer: An all-MLP Architecture for Vision](https://mlsanity.com/paper/2105.01601/) (2021)
- [CoCa: Contrastive Captioners are Image-Text Foundation Models](https://mlsanity.com/paper/2205.01917/) (2022)
- [OK-VQA: A Visual Question Answering Benchmark Requiring External Knowledge](https://mlsanity.com/paper/1906.00067/) (2019)
- [Shikra: Unleashing Multimodal LLM's Referential Dialogue Magic](https://mlsanity.com/paper/2306.15195/) (2023)
- [SPICE: Semantic Propositional Image Caption Evaluation](https://mlsanity.com/paper/1607.08822/) (2016)
- [VideoLLaMA 2: Advancing Spatial-Temporal Modeling and Audio Understanding in Video-LLMs](https://mlsanity.com/paper/2406.07476/) (2024)
- [A-OKVQA: A Benchmark for Visual Question Answering using World Knowledge](https://mlsanity.com/paper/2206.01718/) (2022)
- [CogVLM: Visual Expert for Pretrained Language Models](https://mlsanity.com/paper/2311.03079/) (2023)
- [GIT: A Generative Image-to-text Transformer for Vision and Language](https://mlsanity.com/paper/2205.14100/) (2022)
- [VideoPoet: A Large Language Model for Zero-Shot Video Generation](https://mlsanity.com/paper/2312.14125/) (2023)
- [PointLLM: Empowering Large Language Models to Understand Point Clouds](https://mlsanity.com/paper/2308.16911/) (2023)
- [Scene Text Visual Question Answering](https://mlsanity.com/paper/1905.13648/) (2019)
- [InternLM-XComposer: A Vision-Language Large Model for Advanced Text-image Comprehension and Composition](https://mlsanity.com/paper/2309.15112/) (2023)
- [Visual Spatial Reasoning](https://mlsanity.com/paper/2205.00363/) (2022)

## Built on by (most cited first, 14 of 14)

- [A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers](https://mlsanity.com/paper/2508.21148/) (2025)
- [fMRI-LM: Towards a Universal Foundation Model for Language-Aligned fMRI Understanding](https://mlsanity.com/paper/2511.21760/) (2025)
- [Decoding the Multimodal Mind: Generalizable Brain-to-Text Translation via Multimodal Alignment and Adaptive Routing](https://mlsanity.com/paper/2505.10356/) (2025)
- [RephQA: Evaluating Readability of Large Language Models in Public Health Question Answering](https://mlsanity.com/paper/2509.16360/) (2025)
- [Improving Multimodal Brain Encoding Model with Dynamic Subject-awareness Routing](https://mlsanity.com/paper/2510.04670/) (2025)
- [Decoding Neural Emotion Patterns through Large Language Model Embeddings](https://mlsanity.com/paper/2508.09337/) (2025)
- [Beyond Grid-Locked Voxels: Neural Response Functions for Continuous Brain Encoding](https://mlsanity.com/paper/2510.07342/) (2025)
- [Seeing Through the Brain: New Insights from Decoding Visual Stimuli with fMRI](https://mlsanity.com/paper/2510.16196/) (2025)
- [Unified Multimodal Brain Decoding via Cross-Subject Soft-ROI Fusion](https://mlsanity.com/paper/2512.20249/) (2025)
- [BrainVista: Modeling Naturalistic Brain Dynamics as Multimodal Next-Token Prediction](https://mlsanity.com/paper/2602.04512/) (2026)
- [Sci-CoE: Co-evolving Scientific Reasoning LLMs via Geometric Consensus with Sparse Supervision](https://mlsanity.com/paper/2602.12164/) (2026)
- [Brain-IT-VQA: From Brain Signals to Answers](https://mlsanity.com/paper/2605.29588/) (2026)
- [MindAlign: Decoding Inner Speech from fMRI Signals via Multimodal Embedding Alignment under Limited Data](https://mlsanity.com/paper/2606.20696/) (2026)
- [BrainJanus: A Unified Model for Understanding and Generation across Brain, Vision, and Language](https://mlsanity.com/paper/2606.30319/) (2026)

## Abstract (arXiv)

Decoding functional magnetic resonance imaging (fMRI) signals into text has been a key challenge in the neuroscience community, with the potential to advance brain-computer interfaces and uncover deeper insights into brain mechanisms. However, existing approaches often struggle with suboptimal predictive performance, limited task variety, and poor generalization across subjects. In response to this, we propose MindLLM, a model designed for subject-agnostic and versatile fMRI-to-text decoding. MindLLM consists of an fMRI encoder and an off-the-shelf LLM. The fMRI encoder employs a neuroscience-informed attention mechanism, which is capable of accommodating subjects with varying input shapes and thus achieves high-performance subject-agnostic decoding. Moreover, we introduce Brain Instruction Tuning (BIT), a novel approach that enhances the model's ability to capture diverse semantic representations from fMRI signals, facilitating more versatile decoding. We evaluate MindLLM on comprehensive fMRI-to-text benchmarks. Results demonstrate that our model outperforms the baselines, improving downstream tasks by 12.0%, unseen subject generalization by 24.5%, and novel task adaptation by 25.0%. Furthermore, the attention patterns in MindLLM provide interpretable insights into its decision-making process.