# DAM-Seg: Anatomically accurate cardiac segmentation using Dense Associative Networks

arXiv: https://arxiv.org/abs/2502.15128 · HTML: https://mlsanity.com/paper/2502.15128/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 24 of its 47 references that are in the map.
- First posted on arXiv 21 Feb 2025.

## Builds on (most cited first, 24 of 24)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Intriguing properties of neural networks](https://mlsanity.com/paper/1312.6199/) (2013)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [Vision Transformers for Dense Prediction](https://mlsanity.com/paper/2103.13413/) (2021)
- [Deep Neural Networks are Easily Fooled: High Confidence Predictions for Unrecognizable Images](https://mlsanity.com/paper/1412.1897/) (2014)
- [Hopfield Networks is All You Need](https://mlsanity.com/paper/2008.02217/) (2020)
- [nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentation](https://mlsanity.com/paper/1809.10486/) (2018)
- [Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiography](https://mlsanity.com/paper/1908.06948/) (2019)
- [Dense Associative Memory for Pattern Recognition](https://mlsanity.com/paper/1606.01164/) (2016)
- [Large Associative Memory Problem in Neurobiology and Machine Learning](https://mlsanity.com/paper/2008.06996/) (2020)
- [Memformer: A Memory-Augmented Transformer for Sequence Modeling](https://mlsanity.com/paper/2010.06891/) (2020)
- [Universal Hopfield Networks: A General Framework for Single-Shot Associative Memory Models](https://mlsanity.com/paper/2202.04557/) (2022)
- [Modern Hopfield Networks and Attention for Immune Repertoire Classification](https://mlsanity.com/paper/2007.13505/) (2020)
- [Cardiac Segmentation with Strong Anatomical Guarantees](https://mlsanity.com/paper/2006.08825/) (2020)
- [CANet: An Unsupervised Intrusion Detection System for High Dimensional CAN Bus Data](https://mlsanity.com/paper/1906.02492/) (2019)
- [Extending nnU-Net is all you need](https://mlsanity.com/paper/2208.10791/) (2022)
- [GraphEcho: Graph-Driven Unsupervised Domain Adaptation for Echocardiogram Video Segmentation](https://mlsanity.com/paper/2309.11145/) (2023)
- [Segmentation and Vascular Vectorization for Coronary Artery by Geometry-based Cascaded Neural Network](https://mlsanity.com/paper/2305.04208/) (2023)
- [Recurrent Action Transformer with Memory](https://mlsanity.com/paper/2306.09459/) (2023)
- [A Fully Convolutional Neural Network for Cardiac Segmentation in Short-Axis MRI](https://mlsanity.com/paper/1604.00494/) (2016)
- [Anatomically-aware Uncertainty for Semi-supervised Image Segmentation](https://mlsanity.com/paper/2310.16099/) (2023)
- [CardiacNet: Learning to Reconstruct Abnormalities for Cardiac Disease Assessment from Echocardiogram Videos](https://mlsanity.com/paper/2410.20769/) (2024)
- [An Anatomy-aware Framework for Automatic Segmentation of Parotid Tumor from Multimodal MRI](https://mlsanity.com/paper/2210.01467/) (2022)
- [Towards Robust Cardiac Segmentation using Graph Convolutional Networks](https://mlsanity.com/paper/2310.01210/) (2023)

## Built on by (most cited first, 3 of 3)

- [Anatomical Prior-Driven Framework for Autonomous Robotic Cardiac Ultrasound Standard View Acquisition](https://mlsanity.com/paper/2603.21134/) (2026)
- [Contour-Guided Query-Based Feature Fusion for Boundary-Aware and Generalizable Cardiac Ultrasound Segmentation](https://mlsanity.com/paper/2603.28110/) (2026)
- [Compute-Optimal Network Design for Echocardiography Myocardial Segmentation and Perfusion Quantification using Neural Scaling Laws](https://mlsanity.com/paper/2606.06725/) (2026)

## Abstract (arXiv)

Deep learning-based cardiac segmentation has seen significant advancements over the years. Many studies have tackled the challenge of anatomically incorrect segmentation predictions by introducing auxiliary modules. These modules either post-process segmentation outputs or enforce consistency between specific points to ensure anatomical correctness. However, such approaches often increase network complexity, require separate training for these modules, and may lack robustness in scenarios with poor visibility. To address these limitations, we propose a novel transformer-based architecture that leverages dense associative networks to learn and retain specific patterns inherent to cardiac inputs. Unlike traditional methods, our approach restricts the network to memorize a limited set of patterns. During forward propagation, a weighted sum of these patterns is used to enforce anatomical correctness in the output. Since these patterns are input-independent, the model demonstrates enhanced robustness, even in cases with poor visibility. The proposed pipeline was evaluated on two publicly available datasets, CAMUS and CardiacNet. Experimental results indicate that our model consistently outperforms baseline approaches across all metrics, highlighting its effectiveness and reliability for cardiac segmentation tasks.
