# SearchRAG: Can Search Engines Be Helpful for LLM-based Medical Question Answering?

arXiv: https://arxiv.org/abs/2502.13233 · HTML: https://mlsanity.com/paper/2502.13233/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Builds on 28 of its 44 references that are in the map.
- First posted on arXiv 18 Feb 2025.

## Builds on (most cited first, 28 of 28)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [The Pile: An 800GB Dataset of Diverse Text for Language Modeling](https://mlsanity.com/paper/2101.00027/) (2020)
- [REALM: Retrieval-Augmented Language Model Pre-Training](https://mlsanity.com/paper/2002.08909/) (2020)
- [Self-RAG: Learning to Retrieve, Generate, and Critique through Self-Reflection](https://mlsanity.com/paper/2310.11511/) (2023)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [Large Language Monkeys: Scaling Inference Compute with Repeated Sampling](https://mlsanity.com/paper/2407.21787/) (2024)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [Adaptive-RAG: Learning to Adapt Retrieval-Augmented Large Language Models through Question Complexity](https://mlsanity.com/paper/2403.14403/) (2024)
- [Making Retrieval-Augmented Language Models Robust to Irrelevant Context](https://mlsanity.com/paper/2310.01558/) (2023)
- [KEPLER: A Unified Model for Knowledge Embedding and Pre-trained Language Representation](https://mlsanity.com/paper/1911.06136/) (2019)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [The Power of Noise: Redefining Retrieval for RAG Systems](https://mlsanity.com/paper/2401.14887/) (2024)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [Query Rewriting for Retrieval-Augmented Large Language Models](https://mlsanity.com/paper/2305.14283/) (2023)
- [InstructRAG: Instructing Retrieval-Augmented Generation via Self-Synthesized Rationales](https://mlsanity.com/paper/2406.13629/) (2024)
- [ChatQA: Surpassing GPT-4 on Conversational QA and RAG](https://mlsanity.com/paper/2401.10225/) (2024)
- [Instruction Pre-Training: Language Models are Supervised Multitask Learners](https://mlsanity.com/paper/2406.14491/) (2024)
- [Improving Retrieval-Augmented Generation in Medicine with Iterative Follow-up Questions](https://mlsanity.com/paper/2408.00727/) (2024)
- [Rationale-Guided Retrieval Augmented Generation for Medical Question Answering](https://mlsanity.com/paper/2411.00300/) (2024)
- [SimRAG: Self-Improving Retrieval-Augmented Generation for Adapting Large Language Models to Specialized Domains](https://mlsanity.com/paper/2410.17952/) (2024)
- [Retrieval-enhanced Knowledge Editing in Language Models for Multi-Hop Question Answering](https://mlsanity.com/paper/2403.19631/) (2024)
- [UncertaintyRAG: Span-Level Uncertainty Enhanced Long-Context Modeling for Retrieval-Augmented Generation](https://mlsanity.com/paper/2410.02719/) (2024)
- [Understanding the Impact of Confidence in Retrieval Augmented Generation: A Case Study in the Medical Domain](https://mlsanity.com/paper/2412.20309/) (2024)

## Built on by (most cited first, 9 of 9)

- [Can Knowledge-Graph-based Retrieval Augmented Generation Really Retrieve What You Need?](https://mlsanity.com/paper/2510.16582/) (2025)
- [CrashSage: A Large Language Model-Centered Framework for Contextual and Interpretable Traffic Crash Analysis](https://mlsanity.com/paper/2505.07853/) (2025)
- [Build AI Assistants using Large Language Models and Agents to Enhance the Engineering Education of Biomechanics](https://mlsanity.com/paper/2511.15752/) (2025)
- [From Retrieval to Generation: Unifying External and Parametric Knowledge for Medical Question Answering](https://mlsanity.com/paper/2510.18297/) (2025)
- [UETQuintet at BioCreative IX -- MedHopQA: Enhancing Biomedical QA with Selective Multi-hop Reasoning and Contextual Retrieval](https://mlsanity.com/paper/2601.06974/) (2026)
- [Less Data Approximates More: Earning Faithful Confidence in High-Stakes Domains](https://mlsanity.com/paper/2604.08454/) (2026)
- [The Periodic Table of LLM Reasoning: A Structured Survey of Reasoning Paradigms, Methods, and Failure Modes](https://mlsanity.com/paper/2606.11470/) (2026)
- [TRACE: Agentic Catalog Enrichment with Multi-source Evidence Grounding](https://mlsanity.com/paper/2608.20844/) (2026)
- [Mapping the RAG Landscape: A Four Axis Taxonomy of Efficiency, Defense, Interactivity, and Reasoning](https://mlsanity.com/paper/2610.01936/) (2026)

## Abstract (arXiv)

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external information from static knowledge bases, which can be outdated or incomplete, missing fine-grained clinical details essential for accurate medical question answering. In this work, we propose SearchRAG, a novel framework that overcomes these limitations by leveraging real-time search engines. Our method employs synthetic query generation to convert complex medical questions into search-engine-friendly queries and utilizes uncertainty-based knowledge selection to filter and incorporate the most relevant and informative medical knowledge into the LLM's input. Experimental results demonstrate that our method significantly improves response accuracy in medical question answering tasks, particularly for complex questions requiring detailed and up-to-date knowledge.