# A Physics-Informed Deep Learning Model for MRI Brain Motion Correction

arXiv: https://arxiv.org/abs/2502.09296 · HTML: https://mlsanity.com/paper/2502.09296/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 43 references that are in the map.
- First posted on arXiv 13 Feb 2025.

## Builds on (most cited first, 13 of 13)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [SwinIR: Image Restoration Using Swin Transformer](https://mlsanity.com/paper/2108.10257/) (2021)
- [A review of deep learning in medical imaging: Imaging traits, technology trends, case studies with progress highlights, and future promises](https://mlsanity.com/paper/2008.09104/) (2020)
- [Medical Image Segmentation Review: The success of U-Net](https://mlsanity.com/paper/2211.14830/) (2022)
- [Efficient Diffusion Model for Image Restoration by Residual Shifting](https://mlsanity.com/paper/2403.07319/) (2024)
- [PyTorch Image Quality: Metrics for Image Quality Assessment](https://mlsanity.com/paper/2208.14818/) (2022)
- [Learning MRI Artifact Removal With Unpaired Data](https://mlsanity.com/paper/2110.04604/) (2021)
- [ASPS: Augmented Segment Anything Model for Polyp Segmentation](https://mlsanity.com/paper/2407.00718/) (2024)
- [Exploring Frequency-Inspired Optimization in Transformer for Efficient Single Image Super-Resolution](https://mlsanity.com/paper/2308.05022/) (2023)
- [Self-Supervised Adversarial Diffusion Models for Fast MRI Reconstruction](https://mlsanity.com/paper/2406.15656/) (2024)
- [SISMIK for brain MRI: Deep-learning-based motion estimation and model-based motion correction in k-space](https://mlsanity.com/paper/2312.13220/) (2023)
- [T1-contrast Enhanced MRI Generation from Multi-parametric MRI for Glioma Patients with Latent Tumor Conditioning](https://mlsanity.com/paper/2409.01622/) (2024)

## Built on by (most cited first, 4 of 4)

- [Res-MoCoDiff: Residual-guided diffusion models for motion artifact correction in brain MRI](https://mlsanity.com/paper/2505.03498/) (2025)
- [Hallucination in Medical Imaging AI: A Cross-Modality Analytical Framework for Taxonomy, Detection, and Mitigation under Regulatory Constraints](https://mlsanity.com/paper/2606.13211/) (2026)
- [Motion Artifact-Aware Self-Supervised Representation Learning for 3D Brain MRI Motion Artifact Reduction](https://mlsanity.com/paper/2608.10170/) (2026)
- [Evaluating the Safety of Deep Learning-Based Brain MRI Reconstruction](https://mlsanity.com/paper/2608.28714/) (2026)

## Abstract (arXiv)

Background: MRI is crucial for brain imaging but is highly susceptible to motion artifacts due to long acquisition times. This study introduces PI-MoCoNet, a physics-informed motion correction network that integrates spatial and k-space information to remove motion artifacts without explicit motion parameter estimation, enhancing image fidelity and diagnostic reliability. Materials and Methods: PI-MoCoNet consists of a motion detection network (U-net with spatial averaging) to identify corrupted k-space lines and a motion correction network (U-net with Swin Transformer blocks) to reconstruct motion-free images. The correction is guided by three loss functions: reconstruction (L1), perceptual (LPIPS), and data consistency (Ldc). Motion artifacts were simulated via rigid phase encoding perturbations and evaluated on IXI and MR-ART datasets against Pix2Pix, CycleGAN, and U-net using PSNR, SSIM, and NMSE. Results: PI-MoCoNet significantly improved image quality. On IXI, for minor artifacts, PSNR increased from 34.15 dB to 45.95 dB, SSIM from 0.87 to 1.00, and NMSE reduced from 0.55% to 0.04%. For moderate artifacts, PSNR improved from 30.23 dB to 42.16 dB, SSIM from 0.80 to 0.99, and NMSE from 1.32% to 0.09%. For heavy artifacts, PSNR rose from 27.99 dB to 36.01 dB, SSIM from 0.75 to 0.97, and NMSE decreased from 2.21% to 0.36%. On MR-ART, PI-MoCoNet achieved PSNR gains of ~10 dB and SSIM improvements of up to 0.20, with NMSE reductions of ~6%. Ablation studies confirmed the importance of data consistency and perceptual losses, yielding a 1 dB PSNR gain and 0.17% NMSE reduction. Conclusions: PI-MoCoNet effectively mitigates motion artifacts in brain MRI, outperforming existing methods. Its ability to integrate spatial and k-space information makes it a promising tool for clinical use in motion-prone settings. Code: https://github.com/mosaf/PI-MoCoNet.git.
