# Disentangling Total-Variance and Signal-to-Noise-Ratio Improves Diffusion Models

arXiv: https://arxiv.org/abs/2502.08598 · HTML: https://mlsanity.com/paper/2502.08598/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Placed in Diffusion foundations and sampling, one of 14 directions in Diffusion models.
- Builds on 52 of its 61 references that are in the map.
- First posted on arXiv 12 Feb 2025.

## Placed in

- Diffusion models / [Diffusion foundations and sampling](https://mlsanity.com/diffusion/diffusion-foundations-and-sampling/)

## Builds on (most cited first, 30 of 52)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Scalable Diffusion Models with Transformers](https://mlsanity.com/paper/2212.09748/) (2022)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Flow Matching for Generative Modeling](https://mlsanity.com/paper/2210.02747/) (2022)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Flow Straight and Fast: Learning to Generate and Transfer Data with Rectified Flow](https://mlsanity.com/paper/2209.03003/) (2022)
- [GLIDE: Towards Photorealistic Image Generation and Editing with Text-Guided Diffusion Models](https://mlsanity.com/paper/2112.10741/) (2021)
- [Elucidating the Design Space of Diffusion-Based Generative Models](https://mlsanity.com/paper/2206.00364/) (2022)
- [DPM-Solver: A Fast ODE Solver for Diffusion Probabilistic Model Sampling in Around 10 Steps](https://mlsanity.com/paper/2206.00927/) (2022)
- [Consistency Models](https://mlsanity.com/paper/2303.01469/) (2023)
- [DiffWave: A Versatile Diffusion Model for Audio Synthesis](https://mlsanity.com/paper/2009.09761/) (2020)
- [Variational Diffusion Models](https://mlsanity.com/paper/2107.00630/) (2021)
- [StarGAN v2: Diverse Image Synthesis for Multiple Domains](https://mlsanity.com/paper/1912.01865/) (2019)
- [Improved Techniques for Training Score-Based Generative Models](https://mlsanity.com/paper/2006.09011/) (2020)
- [Building Normalizing Flows with Stochastic Interpolants](https://mlsanity.com/paper/2209.15571/) (2022)
- [DPM-Solver++: Fast Solver for Guided Sampling of Diffusion Probabilistic Models](https://mlsanity.com/paper/2211.01095/) (2022)
- [Improving and generalizing flow-based generative models with minibatch optimal transport](https://mlsanity.com/paper/2302.00482/) (2023)
- [SiT: Exploring Flow and Diffusion-based Generative Models with Scalable Interpolant Transformers](https://mlsanity.com/paper/2401.08740/) (2024)
- [Pseudo Numerical Methods for Diffusion Models on Manifolds](https://mlsanity.com/paper/2202.09778/) (2022)
- [Equivariant Diffusion for Molecule Generation in 3D](https://mlsanity.com/paper/2203.17003/) (2022)
- [WaveGrad: Estimating Gradients for Waveform Generation](https://mlsanity.com/paper/2009.00713/) (2020)
- [AudioLDM: Text-to-Audio Generation with Latent Diffusion Models](https://mlsanity.com/paper/2301.12503/) (2023)
- [Fast Sampling of Diffusion Models with Exponential Integrator](https://mlsanity.com/paper/2204.13902/) (2022)
- [GeoDiff: a Geometric Diffusion Model for Molecular Conformation Generation](https://mlsanity.com/paper/2203.02923/) (2022)

## Built on by (most cited first, 4 of 4)

- [Control Variate Score Matching for Diffusion Models](https://mlsanity.com/paper/2512.20003/) (2025)
- [Generative Pseudo-Force Fields for Molecular Generation](https://mlsanity.com/paper/2605.19050/) (2026)
- [ReactionAtlas: Ab origine exploration of chemical reaction networks with machine learning](https://mlsanity.com/paper/2606.30778/) (2026)
- [Universal Local Error and Realized Amplification for the First-Order EDM Predictor](https://mlsanity.com/paper/2610.10190/) (2026)

## Abstract (arXiv)

Diffusion models have been widely adopted as a powerful generative framework across numerous scientific domains, yet their inherently iterative sampling process remains a significant computational bottleneck. While this is typically mitigated by reducing the number of reverse diffusion steps, sample quality becomes highly sensitive to the chosen noise schedule, i.e. the manner in which noise is introduced and the signal is reduced at each step. Although prior work has improved on the original variance-preserving and variance-exploding schedules, these approaches passively adjust the total variance, without direct independent control over it. In this work, we propose a novel total-variance/signal-to-noise-ratio disentangled (TV/SNR) framework, where TV and SNR can be controlled independently. Our approach reveals that schedules with exponentially exploding TV can be consistently improved by adopting a constant TV schedule while preserving the underlying SNR schedule. Furthermore, we demonstrate that generalizing the SNR schedule of optimal transport flow matching significantly enhances generation efficiency. Crucially, these gains remain consistent across various reverse diffusion solvers and reduce the search space to two independent and interpretable parameters, enabling fast and robust sampling for complex scientific applications, such as molecular structure generation.
