# KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level

arXiv: https://arxiv.org/abs/2502.07288 · HTML: https://mlsanity.com/paper/2502.07288/

## Key facts

- Cited by 7 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 11 Feb 2025.

## Built on by (most cited first, 7 of 7)

- [K-Prism: A Knowledge-Guided and Prompt Integrated Universal Medical Image Segmentation Model](https://mlsanity.com/paper/2509.25594/) (2025)
- [VISTA-PATH: An interactive foundation model for pathology image segmentation and quantitative analysis in computational pathology](https://mlsanity.com/paper/2601.16451/) (2026)
- [PathSeqSAM: Sequential Modeling for Pathology Image Segmentation with SAM2](https://mlsanity.com/paper/2504.10526/) (2025)
- [RefineSeg: Dual Coarse-to-Fine Learning for Medical Image Segmentation](https://mlsanity.com/paper/2508.02844/) (2025)
- [Controllable Diffusion-Based Lesion Inpainting for Scalable Histopathology Data Augmentation](https://mlsanity.com/paper/2601.08127/) (2026)
- [MORI-Seg: Learning Morphological Geometry for Instance Segmentation without Instance Annotations](https://mlsanity.com/paper/2605.28261/) (2026)
- [CoordFormer: Give Me Any Coordinates and I Will Give You Labels](https://mlsanity.com/paper/2609.08660/) (2026)

## Abstract (arXiv)

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive benchmarks for kidney pathology segmentation hinders progress in the field. To address this, we organized the Kidney Pathology Image Segmentation (KPIs) Challenge, introducing a dataset that incorporates preclinical rodent models of CKD with over 10,000 annotated glomeruli from 60+ Periodic Acid Schiff (PAS)-stained whole slide images. The challenge includes two tasks, patch-level segmentation and whole slide image segmentation and detection, evaluated using the Dice Similarity Coefficient (DSC) and F1-score. By encouraging innovative segmentation methods that adapt to diverse CKD models and tissue conditions, the KPIs Challenge aims to advance kidney pathology analysis, establish new benchmarks, and enable precise, large-scale quantification for disease research and diagnosis.