# ELMTEX: Fine-Tuning Large Language Models for Structured Clinical Information Extraction. A Case Study on Clinical Reports

arXiv: https://arxiv.org/abs/2502.05638 · HTML: https://mlsanity.com/paper/2502.05638/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 29 references that are in the map.
- First posted on arXiv 8 Feb 2025.

## Builds on (most cited first, 13 of 13)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Survey of Hallucination in Natural Language Generation](https://mlsanity.com/paper/2202.03629/) (2022)
- [Med-HALT: Medical Domain Hallucination Test for Large Language Models](https://mlsanity.com/paper/2307.15343/) (2023)
- [ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluation](https://mlsanity.com/paper/2306.09968/) (2023)
- [Parameter-Efficient Fine-Tuning of LLaMA for the Clinical Domain](https://mlsanity.com/paper/2307.03042/) (2023)
- [GPT-3 Models are Poor Few-Shot Learners in the Biomedical Domain](https://mlsanity.com/paper/2109.02555/) (2021)
- [Model Tuning or Prompt Tuning? A Study of Large Language Models for Clinical Concept and Relation Extraction](https://mlsanity.com/paper/2310.06239/) (2023)
- [Ground Truth Or Dare: Factors Affecting The Creation Of Medical Datasets For Training AI](https://mlsanity.com/paper/2309.12327/) (2023)
- [Natural language processing of MIMIC-III clinical notes for identifying diagnosis and procedures with neural networks](https://mlsanity.com/paper/1912.12397/) (2019)
- [Intimate Partner Violence and Injury Prediction From Radiology Reports](https://mlsanity.com/paper/2009.09084/) (2020)
- [A Medical Information Extraction Workbench to Process German Clinical Text](https://mlsanity.com/paper/2207.03885/) (2022)

## Built on by (most cited first, 2 of 2)

- [AutoMedPrompt: A New Framework for Optimizing LLM Medical Prompts Using Textual Gradients](https://mlsanity.com/paper/2502.15944/) (2025)
- [Benchmarking and Adapting On-Device LLMs for Clinical Decision Support](https://mlsanity.com/paper/2601.03266/) (2025)

## Abstract (arXiv)

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large Language Models (LLMs) to extract structured information from unstructured clinical reports, focusing on patient history, diagnoses, treatments, and other predefined categories. We developed a workflow with a user interface and evaluated LLMs of varying sizes through prompting strategies and fine-tuning. Our results show that fine-tuned smaller models match or surpass larger counterparts in performance, offering efficiency for resource-limited settings. A new dataset of 60,000 annotated English clinical summaries and 24,000 German translations was validated with automated and manual checks. The evaluations used ROUGE, BERTScore, and entity-level metrics. The work highlights the approach's viability and outlines future improvements.
