# Position: Multimodal Large Language Models Can Significantly Advance Scientific Reasoning

arXiv: https://arxiv.org/abs/2502.02871 · HTML: https://mlsanity.com/paper/2502.02871/

## Key facts

- Cited by 33 papers in the map (data through 14 Oct 2026).
- Placed in Multimodal reasoning, one of 17 directions in LLM reasoning.
- Builds on 199 of its 290 references that are in the map.
- First posted on arXiv 5 Feb 2025.

## Placed in

- LLM reasoning / [Multimodal reasoning](https://mlsanity.com/lr/multimodal-reasoning/)
- Multimodal LLMs / vision-language models / [MLLM training and visual instruction tuning](https://mlsanity.com/mllm/mllm-training-and-visual-instruction-tuning/)

## Builds on (most cited first, 30 of 199)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Models](https://mlsanity.com/paper/2402.03300/) (2024)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Improved Baselines with Visual Instruction Tuning](https://mlsanity.com/paper/2310.03744/) (2023)
- [Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolution](https://mlsanity.com/paper/2409.12191/) (2024)
- [Gemini 1.5: Unlocking multimodal understanding across millions of tokens of context](https://mlsanity.com/paper/2403.05530/) (2024)
- [A Survey of Large Language Models](https://mlsanity.com/paper/2303.18223/) (2023)
- [InternVL: Scaling up Vision Foundation Models and Aligning for Generic Visual-Linguistic Tasks](https://mlsanity.com/paper/2312.14238/) (2023)
- [A Survey on Large Language Model based Autonomous Agents](https://mlsanity.com/paper/2308.11432/) (2023)
- [Qwen-VL: A Versatile Vision-Language Model for Understanding, Localization, Text Reading, and Beyond](https://mlsanity.com/paper/2308.12966/) (2023)
- [MMBench: Is Your Multi-modal Model an All-around Player?](https://mlsanity.com/paper/2307.06281/) (2023)
- [Qwen2 Technical Report](https://mlsanity.com/paper/2407.10671/) (2024)
- [MMMU: A Massive Multi-discipline Multimodal Understanding and Reasoning Benchmark for Expert AGI](https://mlsanity.com/paper/2311.16502/) (2023)
- [Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answering](https://mlsanity.com/paper/2209.09513/) (2022)
- [A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions](https://mlsanity.com/paper/2311.05232/) (2023)
- [The Rise and Potential of Large Language Model Based Agents: A Survey](https://mlsanity.com/paper/2309.07864/) (2023)
- [Solving Quantitative Reasoning Problems with Language Models](https://mlsanity.com/paper/2206.14858/) (2022)
- [Qwen2.5-Coder Technical Report](https://mlsanity.com/paper/2409.12186/) (2024)
- [DeepSeek-Coder: When the Large Language Model Meets Programming -- The Rise of Code Intelligence](https://mlsanity.com/paper/2401.14196/) (2024)
- [OlympiadBench: A Challenging Benchmark for Promoting AGI with Olympiad-Level Bilingual Multimodal Scientific Problems](https://mlsanity.com/paper/2402.14008/) (2024)
- [Qwen2.5-Math Technical Report: Toward Mathematical Expert Model via Self-Improvement](https://mlsanity.com/paper/2409.12122/) (2024)
- [Large Language Models are not Fair Evaluators](https://mlsanity.com/paper/2305.17926/) (2023)
- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [How Far Are We to GPT-4V? Closing the Gap to Commercial Multimodal Models with Open-Source Suites](https://mlsanity.com/paper/2404.16821/) (2024)
- [Math-Shepherd: Verify and Reinforce LLMs Step-by-step without Human Annotations](https://mlsanity.com/paper/2312.08935/) (2023)
- [ExpeL: LLM Agents Are Experiential Learners](https://mlsanity.com/paper/2308.10144/) (2023)
- [Reasoning with Language Model is Planning with World Model](https://mlsanity.com/paper/2305.14992/) (2023)
- [Large Language Models Can Be Easily Distracted by Irrelevant Context](https://mlsanity.com/paper/2302.00093/) (2023)
- [Large Language Model based Multi-Agents: A Survey of Progress and Challenges](https://mlsanity.com/paper/2402.01680/) (2024)

## Built on by (most cited first, 30 of 33)

- [Towards Reasoning Era: A Survey of Long Chain-of-Thought for Reasoning Large Language Models](https://mlsanity.com/paper/2503.09567/) (2025)
- [Thinking with Images for Multimodal Reasoning: Foundations, Methods, and Future Frontiers](https://mlsanity.com/paper/2506.23918/) (2025)
- [A Comprehensive Survey in LLM(-Agent) Full Stack Safety: Data, Training and Deployment](https://mlsanity.com/paper/2504.15585/) (2025)
- [LLM Agents for Education: Advances and Applications](https://mlsanity.com/paper/2503.11733/) (2025)
- [Implicit Reasoning in Large Language Models: A Comprehensive Survey](https://mlsanity.com/paper/2509.02350/) (2025)
- [SafeEraser: Enhancing Safety in Multimodal Large Language Models through Multimodal Machine Unlearning](https://mlsanity.com/paper/2502.12520/) (2025)
- [MMUnlearner: Reformulating Multimodal Machine Unlearning in the Era of Multimodal Large Language Models](https://mlsanity.com/paper/2502.11051/) (2025)
- [Beyond Seeing: Evaluating Multimodal LLMs on Tool-Enabled Image Perception, Transformation, and Reasoning](https://mlsanity.com/paper/2510.12712/) (2025)
- [MathAgent: Leveraging a Mixture-of-Math-Agent Framework for Real-World Multimodal Mathematical Error Detection](https://mlsanity.com/paper/2503.18132/) (2025)
- [DocPruner: A Storage-Efficient Framework for Multi-Vector Visual Document Retrieval via Adaptive Patch-Level Embedding Pruning](https://mlsanity.com/paper/2509.23883/) (2025)
- [GM-PRM: A Generative Multimodal Process Reward Model for Multimodal Mathematical Reasoning](https://mlsanity.com/paper/2508.04088/) (2025)
- [Omni-SimpleMem: Autoresearch-Guided Discovery of Lifelong Multimodal Agent Memory](https://mlsanity.com/paper/2604.01007/) (2026)
- [Evaluating System 1 vs. 2 Reasoning Approaches for Zero-Shot Time Series Forecasting: A Benchmark and Insights](https://mlsanity.com/paper/2503.01895/) (2025)
- [MMSciBench: Benchmarking Language Models on Chinese Multimodal Scientific Problems](https://mlsanity.com/paper/2503.01891/) (2025)
- [NeSyGeo: A Neuro-Symbolic Framework for Multimodal Geometric Reasoning Data Generation](https://mlsanity.com/paper/2505.17121/) (2025)
- [DrVD-Bench: Do Vision-Language Models Reason Like Human Doctors in Medical Image Diagnosis?](https://mlsanity.com/paper/2505.24173/) (2025)
- [Sculpting the Vector Space: Towards Efficient Multi-Vector Visual Document Retrieval via Prune-then-Merge Framework](https://mlsanity.com/paper/2602.19549/) (2026)
- [PhysicsArena: The First Multimodal Physics Reasoning Benchmark Exploring Variable, Process, and Solution Dimensions](https://mlsanity.com/paper/2505.15472/) (2025)
- [Unlocking Multimodal Document Intelligence: From Current Triumphs to Future Frontiers of Visual Document Retrieval](https://mlsanity.com/paper/2602.19961/) (2026)
- [EssayJudge: A Multi-Granular Benchmark for Assessing Automated Essay Scoring Capabilities of Multimodal Large Language Models](https://mlsanity.com/paper/2502.11916/) (2025)
- [CAFES: A Collaborative Multi-Agent Framework for Multi-Granular Multimodal Essay Scoring](https://mlsanity.com/paper/2505.13965/) (2025)
- [EscapeCraft: A 3D Room Escape Environment for Benchmarking Complex Multimodal Reasoning Ability](https://mlsanity.com/paper/2503.10042/) (2025)
- [Knowing the Answer Isn't Enough: Fixing Reasoning Path Failures in LVLMs](https://mlsanity.com/paper/2512.06258/) (2025)
- [DeepSound-V1: Start to Think Step-by-Step in the Audio Generation from Videos](https://mlsanity.com/paper/2503.22208/) (2025)
- [LawThinker: A Deep Research Legal Agent in Dynamic Environments](https://mlsanity.com/paper/2602.12056/) (2026)
- [Reimagining Urban Science: Scaling Causal Inference with Large Language Models](https://mlsanity.com/paper/2504.12345/) (2025)
- [Pierce the Mists, Greet the Sky: Decipher Knowledge Overshadowing via Knowledge Circuit Analysis](https://mlsanity.com/paper/2505.14406/) (2025)
- [MolEmb: Multimodal Large Language Models Can Be Strong Molecular Embedding Models](https://mlsanity.com/paper/2608.23646/) (2026)
- [Unveiling Instruction-Specific Neurons & Experts: An Analytical Framework for LLM's Instruction-Following Capabilities](https://mlsanity.com/paper/2505.21191/) (2025)
- [Parameter Importance-Driven Continual Learning for Foundation Models](https://mlsanity.com/paper/2511.15375/) (2025)

## Abstract (arXiv)

Scientific reasoning, the process through which humans apply logic, evidence, and critical thinking to explore and interpret scientific phenomena, is essential in advancing knowledge reasoning across diverse fields. However, despite significant progress, current scientific reasoning models still struggle with generalization across domains and often fall short of multimodal perception. Multimodal Large Language Models (MLLMs), which integrate text, images, and other modalities, present an exciting opportunity to overcome these limitations and enhance scientific reasoning. Therefore, this position paper argues that MLLMs can significantly advance scientific reasoning across disciplines such as mathematics, physics, chemistry, and biology. First, we propose a four-stage research roadmap of scientific reasoning capabilities, and highlight the current state of MLLM applications in scientific reasoning, noting their ability to integrate and reason over diverse data types. Second, we summarize the key challenges that remain obstacles to achieving MLLM's full potential. To address these challenges, we propose actionable insights and suggestions for the future. Overall, our work offers a novel perspective on MLLM integration with scientific reasoning, providing the LLM community with a valuable vision for achieving Artificial General Intelligence (AGI).