# ConceptVAE: Self-Supervised Fine-Grained Concept Disentanglement from 2D Echocardiographies

arXiv: https://arxiv.org/abs/2502.01335 · HTML: https://mlsanity.com/paper/2502.01335/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 35 of its 49 references that are in the map.
- First posted on arXiv 3 Feb 2025.

## Builds on (most cited first, 30 of 35)

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- [Fast R-CNN](https://mlsanity.com/paper/1504.08083/) (2015)
- [Categorical Reparameterization with Gumbel-Softmax](https://mlsanity.com/paper/1611.01144/) (2016)
- [Generating Diverse High-Fidelity Images with VQ-VAE-2](https://mlsanity.com/paper/1906.00446/) (2019)
- [Semantic Image Synthesis with Spatially-Adaptive Normalization](https://mlsanity.com/paper/1903.07291/) (2019)
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- [Challenging Common Assumptions in the Unsupervised Learning of Disentangled Representations](https://mlsanity.com/paper/1811.12359/) (2018)
- [data2vec: A General Framework for Self-supervised Learning in Speech, Vision and Language](https://mlsanity.com/paper/2202.03555/) (2022)
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- [3D Self-Supervised Methods for Medical Imaging](https://mlsanity.com/paper/2006.03829/) (2020)
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- [Efficient Self-supervised Learning with Contextualized Target Representations for Vision, Speech and Language](https://mlsanity.com/paper/2212.07525/) (2022)
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- [Learning Vision from Models Rivals Learning Vision from Data](https://mlsanity.com/paper/2312.17742/) (2023)
- [Deep Learning for Instance Retrieval: A Survey](https://mlsanity.com/paper/2101.11282/) (2021)
- [Disentangled Representation Learning in Cardiac Image Analysis](https://mlsanity.com/paper/1903.09467/) (2019)
- [Learning Disentangled Representations in the Imaging Domain](https://mlsanity.com/paper/2108.12043/) (2021)
- [ACSeg: Adaptive Conceptualization for Unsupervised Semantic Segmentation](https://mlsanity.com/paper/2210.05944/) (2022)
- [The SSL Interplay: Augmentations, Inductive Bias, and Generalization](https://mlsanity.com/paper/2302.02774/) (2023)
- [SwinMM: Masked Multi-view with Swin Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2307.12591/) (2023)
- [Light-Weight RefineNet for Real-Time Semantic Segmentation](https://mlsanity.com/paper/1810.03272/) (2018)

## Abstract (arXiv)

While traditional self-supervised learning methods improve performance and robustness across various medical tasks, they rely on single-vector embeddings that may not capture fine-grained concepts such as anatomical structures or organs. The ability to identify such concepts and their characteristics without supervision has the potential to improve pre-training methods, and enable novel applications such as fine-grained image retrieval and concept-based outlier detection. In this paper, we introduce ConceptVAE, a novel pre-training framework that detects and disentangles fine-grained concepts from their style characteristics in a self-supervised manner. We present a suite of loss terms and model architecture primitives designed to discretise input data into a preset number of concepts along with their local style. We validate ConceptVAE both qualitatively and quantitatively, demonstrating its ability to detect fine-grained anatomical structures such as blood pools and septum walls from 2D cardiac echocardiographies. Quantitatively, ConceptVAE outperforms traditional self-supervised methods in tasks such as region-based instance retrieval, semantic segmentation, out-of-distribution detection, and object detection. Additionally, we explore the generation of in-distribution synthetic data that maintains the same concepts as the training data but with distinct styles, highlighting its potential for more calibrated data generation. Overall, our study introduces and validates a promising new pre-training technique based on concept-style disentanglement, opening multiple avenues for developing models for medical image analysis that are more interpretable and explainable than black-box approaches.
