# K-COMP: Retrieval-Augmented Medical Domain Question Answering With Knowledge-Injected Compressor

arXiv: https://arxiv.org/abs/2501.13567 · HTML: https://mlsanity.com/paper/2501.13567/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in Medical and biomedical RAG, one of 15 directions in Retrieval-augmented generation.
- Builds on 54 of its 74 references that are in the map.
- First posted on arXiv 23 Jan 2025.

## Placed in

- Retrieval-augmented generation / [Medical and biomedical RAG](https://mlsanity.com/rag/medical-and-biomedical-rag/)

## Builds on (most cited first, 30 of 54)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [BART: Denoising Sequence-to-Sequence Pre-training for Natural Language Generation, Translation, and Comprehension](https://mlsanity.com/paper/1910.13461/) (2019)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [Dense Passage Retrieval for Open-Domain Question Answering](https://mlsanity.com/paper/2004.04906/) (2020)
- [Lost in the Middle: How Language Models Use Long Contexts](https://mlsanity.com/paper/2307.03172/) (2023)
- [The Curious Case of Neural Text Degeneration](https://mlsanity.com/paper/1904.09751/) (2019)
- [Billion-scale similarity search with GPUs](https://mlsanity.com/paper/1702.08734/) (2017)
- [G-Eval: NLG Evaluation using GPT-4 with Better Human Alignment](https://mlsanity.com/paper/2303.16634/) (2023)
- [Self-RAG: Learning to Retrieve, Generate, and Critique through Self-Reflection](https://mlsanity.com/paper/2310.11511/) (2023)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [AWQ: Activation-aware Weight Quantization for LLM Compression and Acceleration](https://mlsanity.com/paper/2306.00978/) (2023)
- [Unsupervised Dense Information Retrieval with Contrastive Learning](https://mlsanity.com/paper/2112.09118/) (2021)
- [GLM: General Language Model Pretraining with Autoregressive Blank Infilling](https://mlsanity.com/paper/2103.10360/) (2021)
- [SpanBERT: Improving Pre-training by Representing and Predicting Spans](https://mlsanity.com/paper/1907.10529/) (2019)
- [REPLUG: Retrieval-Augmented Black-Box Language Models](https://mlsanity.com/paper/2301.12652/) (2023)
- [In-Context Retrieval-Augmented Language Models](https://mlsanity.com/paper/2302.00083/) (2023)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [C-Pack: Packed Resources For General Chinese Embeddings](https://mlsanity.com/paper/2309.07597/) (2023)
- [RAPTOR: Recursive Abstractive Processing for Tree-Organized Retrieval](https://mlsanity.com/paper/2401.18059/) (2024)
- [InCoder: A Generative Model for Code Infilling and Synthesis](https://mlsanity.com/paper/2204.05999/) (2022)
- [How Far Can Camels Go? Exploring the State of Instruction Tuning on Open Resources](https://mlsanity.com/paper/2306.04751/) (2023)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [Generate rather than Retrieve: Large Language Models are Strong Context Generators](https://mlsanity.com/paper/2209.10063/) (2022)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [Towards a Unified Multi-Dimensional Evaluator for Text Generation](https://mlsanity.com/paper/2210.07197/) (2022)
- [Efficient Training of Language Models to Fill in the Middle](https://mlsanity.com/paper/2207.14255/) (2022)

## Built on by (most cited first, 2 of 2)

- [Injecting Domain-Specific Knowledge into Large Language Models: A Comprehensive Survey](https://mlsanity.com/paper/2502.10708/) (2025)
- [MedCoT-RAG: Causal Chain-of-Thought RAG for Medical Question Answering](https://mlsanity.com/paper/2508.15849/) (2025)

## Abstract (arXiv)

Retrieval-augmented question answering (QA) integrates external information and thereby increases the QA accuracy of reader models that lack domain knowledge. However, documents retrieved for closed domains require high expertise, so the reader model may have difficulty fully comprehending the text. Moreover, the retrieved documents contain thousands of tokens, some unrelated to the question. As a result, the documents include some inaccurate information, which could lead the reader model to mistrust the passages and could result in hallucinations. To solve these problems, we propose K-comp (Knowledge-injected compressor) which provides the knowledge required to answer correctly. The compressor automatically generates the prior knowledge necessary to facilitate the answer process prior to compression of the retrieved passages. Subsequently, the passages are compressed autoregressively, with the generated knowledge being integrated into the compression process. This process ensures alignment between the question intent and the compressed context. By augmenting this prior knowledge and concise context, the reader models are guided toward relevant answers and trust the context.