# MyDigiTwin: A Privacy-Preserving Framework for Personalized Cardiovascular Risk Prediction and Scenario Exploration

arXiv: https://arxiv.org/abs/2501.12193 · HTML: https://mlsanity.com/paper/2501.12193/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 47 references that are in the map.
- First posted on arXiv 21 Jan 2025.

## Builds on (most cited first, 9 of 9)

- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Advances and Open Problems in Federated Learning](https://mlsanity.com/paper/1912.04977/) (2019)
- [Federated Optimization in Heterogeneous Networks](https://mlsanity.com/paper/1812.06127/) (2018)
- [An Efficient Framework for Clustered Federated Learning](https://mlsanity.com/paper/2006.04088/) (2020)
- [Clustered Federated Learning: Model-Agnostic Distributed Multi-Task Optimization under Privacy Constraints](https://mlsanity.com/paper/1910.01991/) (2019)
- [Federated Machine Learning: Concept and Applications](https://mlsanity.com/paper/1902.04885/) (2019)
- [DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Network](https://mlsanity.com/paper/1606.00931/) (2016)
- [Heterogeneous Federated Learning: State-of-the-art and Research Challenges](https://mlsanity.com/paper/2307.10616/) (2023)
- [Rethinking Normalization Methods in Federated Learning](https://mlsanity.com/paper/2210.03277/) (2022)

## Built on by (most cited first, 1 of 1)

- [Federated Deep Learning for Privacy-Preserving Cardiovascular Disease Risk Prediction](https://mlsanity.com/paper/2607.08595/) (2026)

## Abstract (arXiv)

Cardiovascular disease (CVD) remains a leading cause of death, and primary prevention through personalized interventions is crucial. This paper introduces MyDigiTwin, a framework that integrates health digital twins with personal health environments to empower patients in exploring personalized health scenarios while ensuring data privacy. MyDigiTwin uses federated learning to train predictive models across distributed datasets without transferring raw data, and a novel data harmonization framework addresses semantic and format inconsistencies in health data. A proof-of-concept demonstrates the feasibility of harmonizing and using cohort data to train privacy-preserving CVD prediction models. This framework offers a scalable solution for proactive, personalized cardiovascular care and sets the stage for future applications in real-world healthcare settings.