# SPM 25: open source neuroimaging analysis software

arXiv: https://arxiv.org/abs/2501.12081 · HTML: https://mlsanity.com/paper/2501.12081/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 21 Jan 2025.

## Built on by (most cited first, 2 of 2)

- [petBrain: A New Pipeline for Amyloid, Tau Tangles and Neurodegeneration Quantification Using PET and MRI](https://mlsanity.com/paper/2506.03217/) (2025)
- [TissUnet: Improved Extracranial Tissue and Cranium Segmentation for Children through Adulthood](https://mlsanity.com/paper/2506.05660/) (2025)

## Abstract (arXiv)

Statistical Parametric Mapping (SPM) is an integrated set of methods for testing hypotheses about the brain's structure and function, using data from imaging devices. These methods are implemented in an open source software package, SPM, which has been in continuous development for more than 30 years by an international community of developers. This paper reports the release of SPM 25.01, a major new version of the software that incorporates novel analysis methods, optimisations of existing methods, as well as improved practices for open science and software development.