# Automated Detection of Epileptic Spikes and Seizures Incorporating a Novel Spatial Clustering Prior

arXiv: https://arxiv.org/abs/2501.10404 · HTML: https://mlsanity.com/paper/2501.10404/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 5 of its 30 references that are in the map.
- First posted on arXiv 5 Jan 2025.

## Builds on (most cited first, 5 of 5)

- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [iTransformer: Inverted Transformers Are Effective for Time Series Forecasting](https://mlsanity.com/paper/2310.06625/) (2023)
- [Learning Spatio-Temporal Features with 3D Residual Networks for Action Recognition](https://mlsanity.com/paper/1708.07632/) (2017)
- [The Temple University Hospital Seizure Detection Corpus](https://mlsanity.com/paper/1801.08085/) (2018)
- [Self-Supervised Graph Neural Networks for Improved Electroencephalographic Seizure Analysis](https://mlsanity.com/paper/2104.08336/) (2021)

## Built on by (most cited first, 1 of 1)

- [IEFS-GMB: Gradient Memory Bank-Guided Feature Selection Based on Information Entropy for EEG Classification of Neurological Disorders](https://mlsanity.com/paper/2509.15259/) (2025)

## Abstract (arXiv)

A Magnetoencephalography (MEG) time-series recording consists of multi-channel signals collected by superconducting sensors, with each signal's intensity reflecting magnetic field changes over time at the sensor location. Automating epileptic MEG spike detection significantly reduces manual assessment time and effort, yielding substantial clinical benefits. Existing research addresses MEG spike detection by encoding neural network inputs with signals from all channel within a time segment, followed by classification. However, these methods overlook simultaneous spiking occurred from nearby sensors. We introduce a simple yet effective paradigm that first clusters MEG channels based on their sensor's spatial position. Next, a novel convolutional input module is designed to integrate the spatial clustering and temporal changes of the signals. This module is fed into a custom MEEG-ResNet3D developed by the authors, which learns to extract relevant features and classify the input as a spike clip or not. Our method achieves an F1 score of 94.73% on a large real-world MEG dataset Sanbo-CMR collected from two centers, outperforming state-of-the-art approaches by 1.85%. Moreover, it demonstrates efficacy and stability in the Electroencephalographic (EEG) seizure detection task, yielding an improved weighted F1 score of 1.4% compared to current state-of-the-art techniques evaluated on TUSZ, whch is the largest EEG seizure dataset.