# LLM4SR: A Survey on Large Language Models for Scientific Research

arXiv: https://arxiv.org/abs/2501.04306 · HTML: https://mlsanity.com/paper/2501.04306/

## Key facts

- Cited by 83 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 8 Jan 2025.

## Built on by (most cited first, 30 of 83)

- [AlphaEvolve: A coding agent for scientific and algorithmic discovery](https://mlsanity.com/paper/2506.13131/) (2025)
- [From AI for Science to Agentic Science: A Survey on Autonomous Scientific Discovery](https://mlsanity.com/paper/2508.14111/) (2025)
- [ResearchBench: Benchmarking LLMs in Scientific Discovery via Inspiration-Based Task Decomposition](https://mlsanity.com/paper/2503.21248/) (2025)
- [MLR-Bench: Evaluating AI Agents on Open-Ended Machine Learning Research](https://mlsanity.com/paper/2505.19955/) (2025)
- [Transforming Science with Large Language Models: A Survey on AI-assisted Scientific Discovery, Experimentation, Content Generation, and Evaluation](https://mlsanity.com/paper/2502.05151/) (2025)
- [Ultra-FineWeb: Efficient Data Filtering and Verification for High-Quality LLM Training Data](https://mlsanity.com/paper/2505.05427/) (2025)
- [A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers](https://mlsanity.com/paper/2508.21148/) (2025)
- [LMR-BENCH: Evaluating LLM Agent's Ability on Reproducing Language Modeling Research](https://mlsanity.com/paper/2506.17335/) (2025)
- [The More You Automate, the Less You See: Hidden Pitfalls of AI Scientist Systems](https://mlsanity.com/paper/2509.08713/) (2025)
- [PiFlow: Principle-Aware Scientific Discovery with Multi-Agent Collaboration](https://mlsanity.com/paper/2505.15047/) (2025)
- [PAG: Multi-Turn Reinforced LLM Self-Correction with Policy as Generative Verifier](https://mlsanity.com/paper/2506.10406/) (2025)
- [PaperBanana: Automating Academic Illustration for AI Scientists](https://mlsanity.com/paper/2601.23265/) (2026)
- [Sparks of Science: Hypothesis Generation Using Structured Paper Data](https://mlsanity.com/paper/2504.12976/) (2025)
- [All That Glitters is Not Novel: Plagiarism in AI Generated Research](https://mlsanity.com/paper/2502.16487/) (2025)
- [RExBench: Can coding agents autonomously implement AI research extensions?](https://mlsanity.com/paper/2506.22598/) (2025)
- [SafeScientist: Toward Risk-Aware Scientific Discoveries by LLM Agents](https://mlsanity.com/paper/2505.23559/) (2025)
- [CacheClip: Accelerating RAG with Effective KV Cache Reuse](https://mlsanity.com/paper/2510.10129/) (2025)
- [MOOSE-Chem2: Exploring LLM Limits in Fine-Grained Scientific Hypothesis Discovery via Hierarchical Search](https://mlsanity.com/paper/2505.19209/) (2025)
- [How Far Are AI Scientists from Changing the World?](https://mlsanity.com/paper/2507.23276/) (2025)
- [Gravity-Bench-v1: A Benchmark on Gravitational Physics Discovery for Agents](https://mlsanity.com/paper/2501.18411/) (2025)
- [InteractiveSurvey: An LLM-based Personalized and Interactive Survey Paper Generation System](https://mlsanity.com/paper/2504.08762/) (2025)
- [What Large Language Models Do Not Talk About: An Empirical Study of Moderation and Censorship Practices](https://mlsanity.com/paper/2504.03803/) (2025)
- [Autonomous Agents for Scientific Discovery: Orchestrating Scientists, Language, Code, and Physics](https://mlsanity.com/paper/2510.09901/) (2025)
- [A Survey of AI Scientists](https://mlsanity.com/paper/2510.23045/) (2025)
- [AI for Auto-Research: Roadmap & User Guide](https://mlsanity.com/paper/2605.18661/) (2026)
- [AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discovery](https://mlsanity.com/paper/2605.23204/) (2026)
- [AtmosSci-Bench: Evaluating the Recent Advance of Large Language Model for Atmospheric Science](https://mlsanity.com/paper/2502.01159/) (2025)
- [PhysicsArena: The First Multimodal Physics Reasoning Benchmark Exploring Variable, Process, and Solution Dimensions](https://mlsanity.com/paper/2505.15472/) (2025)
- [LLLMs: A Data-Driven Survey of Evolving Research on Limitations of Large Language Models](https://mlsanity.com/paper/2505.19240/) (2025)
- [Evolving Roles of LLMs in Scientific Innovation: Assistant, Collaborator, Scientist, and Evaluator](https://mlsanity.com/paper/2507.11810/) (2025)

## Abstract (arXiv)

In recent years, the rapid advancement of Large Language Models (LLMs) has transformed the landscape of scientific research, offering unprecedented support across various stages of the research cycle. This paper presents the first systematic survey dedicated to exploring how LLMs are revolutionizing the scientific research process. We analyze the unique roles LLMs play across four critical stages of research: hypothesis discovery, experiment planning and implementation, scientific writing, and peer reviewing. Our review comprehensively showcases the task-specific methodologies and evaluation benchmarks. By identifying current challenges and proposing future research directions, this survey not only highlights the transformative potential of LLMs, but also aims to inspire and guide researchers and practitioners in leveraging LLMs to advance scientific inquiry. Resources are available at the following repository: https://github.com/du-nlp-lab/LLM4SR