# Hengqin-RA-v1: Advanced Large Language Model for Diagnosis and Treatment of Rheumatoid Arthritis with Dataset based Traditional Chinese Medicine

arXiv: https://arxiv.org/abs/2501.02471 · HTML: https://mlsanity.com/paper/2501.02471/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 36 references that are in the map.
- First posted on arXiv 5 Jan 2025.

## Builds on (most cited first, 17 of 17)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [DeepSeek-V2: A Strong, Economical, and Efficient Mixture-of-Experts Language Model](https://mlsanity.com/paper/2405.04434/) (2024)
- [ChatGLM: A Family of Large Language Models from GLM-130B to GLM-4 All Tools](https://mlsanity.com/paper/2406.12793/) (2024)
- [GLM: General Language Model Pretraining with Autoregressive Blank Infilling](https://mlsanity.com/paper/2103.10360/) (2021)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [Baichuan 2: Open Large-scale Language Models](https://mlsanity.com/paper/2309.10305/) (2023)
- [Bias and Fairness in Large Language Models: A Survey](https://mlsanity.com/paper/2309.00770/) (2023)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [ERNIE 3.0: Large-scale Knowledge Enhanced Pre-training for Language Understanding and Generation](https://mlsanity.com/paper/2107.02137/) (2021)
- [Capabilities of Gemini Models in Medicine](https://mlsanity.com/paper/2404.18416/) (2024)
- [HuaTuo: Tuning LLaMA Model with Chinese Medical Knowledge](https://mlsanity.com/paper/2304.06975/) (2023)
- [PanGu-α: Large-scale Autoregressive Pretrained Chinese Language Models with Auto-parallel Computation](https://mlsanity.com/paper/2104.12369/) (2021)
- [Large language models in healthcare and medical domain: A review](https://mlsanity.com/paper/2401.06775/) (2023)
- [Clinical Camel: An Open Expert-Level Medical Language Model with Dialogue-Based Knowledge Encoding](https://mlsanity.com/paper/2305.12031/) (2023)

## Built on by (most cited first, 1 of 1)

- [Improving TCM Question Answering through Tree-Organized Self-Reflective Retrieval with LLMs](https://mlsanity.com/paper/2502.09156/) (2025)

## Abstract (arXiv)

Large language models (LLMs) primarily trained on English texts, often face biases and inaccuracies in Chinese contexts. Their limitations are pronounced in fields like Traditional Chinese Medicine (TCM), where cultural and clinical subtleties are vital, further hindered by a lack of domain-specific data, such as rheumatoid arthritis (RA). To address these issues, this paper introduces Hengqin-RA-v1, the first large language model specifically tailored for TCM with a focus on diagnosing and treating RA. We also present HQ-GCM-RA-C1, a comprehensive RA-specific dataset curated from ancient Chinese medical literature, classical texts, and modern clinical studies. This dataset empowers Hengqin-RA-v1 to deliver accurate and culturally informed responses, effectively bridging the gaps left by general-purpose models. Extensive experiments demonstrate that Hengqin-RA-v1 outperforms state-of-the-art models, even surpassing the diagnostic accuracy of TCM practitioners in certain cases.