# ProjectedEx: Enhancing Generation in Explainable AI for Prostate Cancer

arXiv: https://arxiv.org/abs/2501.01392 · HTML: https://mlsanity.com/paper/2501.01392/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 22 references that are in the map.
- First posted on arXiv 2 Jan 2025.

## Builds on (most cited first, 6 of 6)

- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [CheXplaining in Style: Counterfactual Explanations for Chest X-rays using StyleGAN](https://mlsanity.com/paper/2207.07553/) (2022)
- [ESA: Annotation-Efficient Active Learning for Semantic Segmentation](https://mlsanity.com/paper/2408.13491/) (2024)
- [MSDet: Receptive Field Enhanced Multiscale Detection for Tiny Pulmonary Nodule](https://mlsanity.com/paper/2409.14028/) (2024)
- [SegStitch: Multidimensional Transformer for Robust and Efficient Medical Imaging Segmentation](https://mlsanity.com/paper/2408.00496/) (2024)
- [SegKAN: High-Resolution Medical Image Segmentation with Long-Distance Dependencies](https://mlsanity.com/paper/2412.19990/) (2024)

## Built on by (most cited first, 6 of 6)

- [MedConv: Convolutions Beat Transformers on Long-Tailed Bone Density Prediction](https://mlsanity.com/paper/2502.00631/) (2025)
- [PathoHR: Breast Cancer Survival Prediction on High-Resolution Pathological Images](https://mlsanity.com/paper/2503.17970/) (2025)
- [SSS: Semi-Supervised SAM-2 with Efficient Prompting for Medical Imaging Segmentation](https://mlsanity.com/paper/2506.08949/) (2025)
- [A Novel Convolutional-Free Method for 3D Medical Imaging Segmentation](https://mlsanity.com/paper/2502.05396/) (2025)
- [3D Medical Imaging Segmentation on Non-Contrast CT](https://mlsanity.com/paper/2503.08361/) (2025)
- [SegTTA: Training-Free Test-Time Augmentation for Zero-Shot Medical Imaging Segmentation](https://mlsanity.com/paper/2604.17451/) (2026)

## Abstract (arXiv)

Prostate cancer, a growing global health concern, necessitates precise diagnostic tools, with Magnetic Resonance Imaging (MRI) offering high-resolution soft tissue imaging that significantly enhances diagnostic accuracy. Recent advancements in explainable AI and representation learning have significantly improved prostate cancer diagnosis by enabling automated and precise lesion classification. However, existing explainable AI methods, particularly those based on frameworks like generative adversarial networks (GANs), are predominantly developed for natural image generation, and their application to medical imaging often leads to suboptimal performance due to the unique characteristics and complexity of medical image. To address these challenges, our paper introduces three key contributions. First, we propose ProjectedEx, a generative framework that provides interpretable, multi-attribute explanations, effectively linking medical image features to classifier decisions. Second, we enhance the encoder module by incorporating feature pyramids, which enables multiscale feedback to refine the latent space and improves the quality of generated explanations. Additionally, we conduct comprehensive experiments on both the generator and classifier, demonstrating the clinical relevance and effectiveness of ProjectedEx in enhancing interpretability and supporting the adoption of AI in medical settings. Code will be released at https://github.com/Richardqiyi/ProjectedEx