# Self-Calibrated Dual Contrasting for Annotation-Efficient Bacteria Raman Spectroscopy Clustering and Classification

arXiv: https://arxiv.org/abs/2412.20060 · HTML: https://mlsanity.com/paper/2412.20060/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 17 of its 44 references that are in the map.
- First posted on arXiv 28 Dec 2024.

## Builds on (most cited first, 17 of 17)

- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Momentum Contrast for Unsupervised Visual Representation Learning](https://mlsanity.com/paper/1911.05722/) (2019)
- [Bootstrap your own latent: A new approach to self-supervised Learning](https://mlsanity.com/paper/2006.07733/) (2020)
- [Exploring Simple Siamese Representation Learning](https://mlsanity.com/paper/2011.10566/) (2020)
- [Supervised Contrastive Learning](https://mlsanity.com/paper/2004.11362/) (2020)
- [FixMatch: Simplifying Semi-Supervised Learning with Consistency and Confidence](https://mlsanity.com/paper/2001.07685/) (2020)
- [MixMatch: A Holistic Approach to Semi-Supervised Learning](https://mlsanity.com/paper/1905.02249/) (2019)
- [Temporal Ensembling for Semi-Supervised Learning](https://mlsanity.com/paper/1610.02242/) (2016)
- [Unsupervised Deep Embedding for Clustering Analysis](https://mlsanity.com/paper/1511.06335/) (2015)
- [Self-supervised Learning: Generative or Contrastive](https://mlsanity.com/paper/2006.08218/) (2020)
- [Contrastive Clustering](https://mlsanity.com/paper/2009.09687/) (2020)
- [A Survey on Deep Semi-supervised Learning](https://mlsanity.com/paper/2103.00550/) (2021)
- [Learning Discrete Representations via Information Maximizing Self-Augmented Training](https://mlsanity.com/paper/1702.08720/) (2017)
- [Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentation](https://mlsanity.com/paper/2207.14191/) (2022)
- [Self-supervised Contrastive Representation Learning for Semi-supervised Time-Series Classification](https://mlsanity.com/paper/2208.06616/) (2022)
- [Deep Convolutional Neural Networks for Raman Spectrum Recognition: A Unified Solution](https://mlsanity.com/paper/1708.09022/) (2017)
- [Rapid identification of pathogenic bacteria using Raman spectroscopy and deep learning](https://mlsanity.com/paper/1901.07666/) (2019)

## Abstract (arXiv)

Raman scattering is based on molecular vibration spectroscopy and provides a powerful technology for pathogenic bacteria diagnosis using the unique molecular fingerprint information of a substance. The integration of deep learning technology has significantly improved the efficiency and accuracy of intelligent Raman spectroscopy (RS) recognition. However, the current RS recognition methods based on deep neural networks still require the annotation of a large amount of spectral data, which is labor-intensive. This paper presents a novel annotation-efficient Self-Calibrated Dual Contrasting (SCDC) method for RS recognition that operates effectively with few or no annotation. Our core motivation is to represent the spectrum from two different perspectives in two distinct subspaces: embedding and category. The embedding perspective captures instance-level information, while the category perspective reflects category-level information. Accordingly, we have implemented a dual contrastive learning approach from two perspectives to obtain discriminative representations, which are applicable for Raman spectroscopy recognition under both unsupervised and semi-supervised learning conditions. Furthermore, a self-calibration mechanism is proposed to enhance robustness. Validation of the identification task on three large-scale bacterial Raman spectroscopy datasets demonstrates that our SCDC method achieves robust recognition performance with very few (5% or 10%) or no annotations, highlighting the potential of the proposed method for biospectral identification in annotation-efficient clinical scenarios.