# Mamba-based Deep Learning Approach for Sleep Staging on a Wireless Multimodal Wearable System without Electroencephalography

arXiv: https://arxiv.org/abs/2412.15947 · HTML: https://mlsanity.com/paper/2412.15947/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Physiological signal modeling, one of 10 directions in State-space sequence models (S4, Mamba).
- Builds on 17 of its 49 references that are in the map.
- First posted on arXiv 20 Dec 2024.

## Placed in

- State-space sequence models (S4, Mamba) / [Physiological signal modeling](https://mlsanity.com/ssm/physiological-signal-modeling/)

## Builds on (most cited first, 17 of 17)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [XGBoost: A Scalable Tree Boosting System](https://mlsanity.com/paper/1603.02754/) (2016)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [Learning Phrase Representations using RNN Encoder-Decoder for Statistical Machine Translation](https://mlsanity.com/paper/1406.1078/) (2014)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [Combining Recurrent, Convolutional, and Continuous-time Models with Linear State-Space Layers](https://mlsanity.com/paper/2110.13985/) (2021)
- [SleepTransformer: Automatic Sleep Staging with Interpretability and Uncertainty Quantification](https://mlsanity.com/paper/2105.11043/) (2021)
- [Automatic Sleep Staging of EEG Signals: Recent Development, Challenges, and Future Directions](https://mlsanity.com/paper/2111.08446/) (2021)
- [Automatic Sleep Stage Scoring with Single-Channel EEG Using Convolutional Neural Networks](https://mlsanity.com/paper/1610.01683/) (2016)
- [SleepPPG-Net: a deep learning algorithm for robust sleep staging from continuous photoplethysmography](https://mlsanity.com/paper/2202.05735/) (2022)
- [Sleep Staging from Electrocardiography and Respiration with Deep Learning](https://mlsanity.com/paper/1908.11463/) (2019)
- [Sleep Stage Classification Based on Multi-level Feature Learning and Recurrent Neural Networks via Wearable Device](https://mlsanity.com/paper/1711.00629/) (2017)
- [BiT-MamSleep: Bidirectional Temporal Mamba for EEG Sleep Staging](https://mlsanity.com/paper/2411.01589/) (2024)
- [MSSC-BiMamba: Multimodal Sleep Stage Classification and Early Diagnosis of Sleep Disorders with Bidirectional Mamba](https://mlsanity.com/paper/2405.20142/) (2024)
- [GBHT: Gradient Boosting Histogram Transform for Density Estimation](https://mlsanity.com/paper/2106.05738/) (2021)

## Built on by (most cited first, 1 of 1)

- [Sleep Apnea Detection on a Wireless Multimodal Wearable Device Without Oxygen Flow Using a Mamba-based Deep Learning Approach](https://mlsanity.com/paper/2512.00989/) (2025)

## Abstract (arXiv)

Study Objectives: We investigate a Mamba-based deep learning approach for sleep staging on signals from ANNE One (Sibel Health, Evanston, IL), a non-intrusive dual-module wireless wearable system measuring chest electrocardiography (ECG), triaxial accelerometry, and chest temperature, and finger photoplethysmography and finger temperature. Methods: We obtained wearable sensor recordings from 357 adults undergoing concurrent polysomnography (PSG) at a tertiary care sleep lab. Each PSG recording was manually scored and these annotations served as ground truth labels for training and evaluation of our models. PSG and wearable sensor data were automatically aligned using their ECG channels with manual confirmation by visual inspection. We trained a Mamba-based recurrent neural network architecture on these recordings. Ensembling of model variants with similar architectures was performed. Results: After ensembling, the model attains a 3-class (wake, non rapid eye movement [NREM] sleep, rapid eye movement [REM] sleep) balanced accuracy of 84.02%, F1 score of 84.23%, Cohen's kappa of 72.89%, and a Matthews correlation coefficient (MCC) score of 73.00%; a 4-class (wake, light NREM [N1/N2], deep NREM [N3], REM) balanced accuracy of 75.30%, F1 score of 74.10%, Cohen's kappa of 61.51%, and MCC score of 61.95%; a 5-class (wake, N1, N2, N3, REM) balanced accuracy of 65.11%, F1 score of 66.15%, Cohen's kappa of 53.23%, MCC score of 54.38%. Conclusions: Our Mamba-based deep learning model can successfully infer major sleep stages from the ANNE One, a wearable system without electroencephalography (EEG), and can be applied to data from adults attending a tertiary care sleep clinic.