# Annotation-Efficient Task Guidance for Medical Segment Anything

arXiv: https://arxiv.org/abs/2412.08575 · HTML: https://mlsanity.com/paper/2412.08575/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 5 of its 19 references that are in the map.
- First posted on arXiv 11 Dec 2024.

## Builds on (most cited first, 5 of 5)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [EVF-SAM: Early Vision-Language Fusion for Text-Prompted Segment Anything Model](https://mlsanity.com/paper/2406.20076/) (2024)
- [Segment Anything Model (SAM) Enhanced Pseudo Labels for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/2305.05803/) (2023)
- [Weakly-Supervised Semantic Segmentation with Image-Level Labels: from Traditional Models to Foundation Models](https://mlsanity.com/paper/2310.13026/) (2023)
- [MaskSAM: Towards Auto-prompt SAM with Mask Classification for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/2403.14103/) (2024)

## Abstract (arXiv)

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual annotation, which can be an expensive, time-consuming, and error-prone process. This signals a need for accurate, automatic, and annotation-efficient methods of training these models. We propose SAM-Mix, a novel multitask learning framework for medical image segmentation that uses class activation maps produced by an auxiliary classifier to guide the predictions of the semi-supervised segmentation branch, which is based on the SAM framework. Experimental evaluations on the public LiTS dataset confirm the effectiveness of SAM-Mix for simultaneous classification and segmentation of the liver from abdominal computed tomography (CT) scans. When trained for 90% fewer epochs on only 50 labeled 2D slices, representing just 0.04% of the available labeled training data, SAM-Mix achieves a Dice improvement of 5.1% over the best baseline model. The generalization results for SAM-Mix are even more impressive, with the same model configuration yielding a 25.4% Dice improvement on a cross-domain segmentation task. Our code is available at https://github.com/tbwa233/SAM-Mix.