# Domain-Specific Translation with Open-Source Large Language Models: Resource-Oriented Analysis

arXiv: https://arxiv.org/abs/2412.05862 · HTML: https://mlsanity.com/paper/2412.05862/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 45 references that are in the map.
- First posted on arXiv 8 Dec 2024.

## Builds on (most cited first, 29 of 29)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks](https://mlsanity.com/paper/1908.10084/) (2019)
- [Efficient Memory Management for Large Language Model Serving with PagedAttention](https://mlsanity.com/paper/2309.06180/) (2023)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [Billion-scale similarity search with GPUs](https://mlsanity.com/paper/1702.08734/) (2017)
- [BLOOM: A 176B-Parameter Open-Access Multilingual Language Model](https://mlsanity.com/paper/2211.05100/) (2022)
- [A Call for Clarity in Reporting BLEU Scores](https://mlsanity.com/paper/1804.08771/) (2018)
- [COMET: A Neural Framework for MT Evaluation](https://mlsanity.com/paper/2009.09025/) (2020)
- [Improving Neural Machine Translation Models with Monolingual Data](https://mlsanity.com/paper/1511.06709/) (2015)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [CometKiwi: IST-Unbabel 2022 Submission for the Quality Estimation Shared Task](https://mlsanity.com/paper/2209.06243/) (2022)
- [In-context Examples Selection for Machine Translation](https://mlsanity.com/paper/2212.02437/) (2022)
- [Prompting PaLM for Translation: Assessing Strategies and Performance](https://mlsanity.com/paper/2211.09102/) (2022)
- [MetricX-24: The Google Submission to the WMT 2024 Metrics Shared Task](https://mlsanity.com/paper/2410.03983/) (2024)
- [Document-Level Machine Translation with Large Language Models](https://mlsanity.com/paper/2304.02210/) (2023)
- [A Paradigm Shift in Machine Translation: Boosting Translation Performance of Large Language Models](https://mlsanity.com/paper/2309.11674/) (2023)
- [Dictionary-based Phrase-level Prompting of Large Language Models for Machine Translation](https://mlsanity.com/paper/2302.07856/) (2023)
- [TICO-19: the Translation Initiative for Covid-19](https://mlsanity.com/paper/2007.01788/) (2020)
- [Adaptive Machine Translation with Large Language Models](https://mlsanity.com/paper/2301.13294/) (2023)
- [Steering Large Language Models for Machine Translation with Finetuning and In-Context Learning](https://mlsanity.com/paper/2310.13448/) (2023)
- [AfriMTE and AfriCOMET: Enhancing COMET to Embrace Under-resourced African Languages](https://mlsanity.com/paper/2311.09828/) (2023)
- [ChatGPT MT: Competitive for High- (but not Low-) Resource Languages](https://mlsanity.com/paper/2309.07423/) (2023)
- [The Fine-Tuning Paradox: Boosting Translation Quality Without Sacrificing LLM Abilities](https://mlsanity.com/paper/2405.20089/) (2024)
- [Fine-tuning Large Language Models for Adaptive Machine Translation](https://mlsanity.com/paper/2312.12740/) (2023)
- [Domain Terminology Integration into Machine Translation: Leveraging Large Language Models](https://mlsanity.com/paper/2310.14451/) (2023)
- [A Large Parallel Corpus of Full-Text Scientific Articles](https://mlsanity.com/paper/1905.01852/) (2019)
- [Domain-Specific Text Generation for Machine Translation](https://mlsanity.com/paper/2208.05909/) (2022)

## Built on by (most cited first, 3 of 3)

- [Leveraging Open-Source Large Language Models for Clinical Information Extraction in Resource-Constrained Settings](https://mlsanity.com/paper/2507.20859/) (2025)
- [AfriNLLB: Efficient Translation Models for African Languages](https://mlsanity.com/paper/2602.09373/) (2026)
- [Comparing Large Language Models and Traditional Machine Translation Tools for Translating Medical Consultation Summaries: A Pilot Study](https://mlsanity.com/paper/2504.16601/) (2025)

## Abstract (arXiv)

In this work, we compare the domain-specific translation performance of open-source autoregressive decoder-only large language models (LLMs) with task-oriented machine translation (MT) models. Our experiments focus on the medical domain and cover four language directions with varied resource availability: English-to-French, English-to-Portuguese, English-to-Swahili, and Swahili-to-English. Despite recent advancements, LLMs demonstrate a significant quality gap in specialized translation compared to multilingual encoder-decoder MT models such as NLLB-200. Our results indicate that NLLB-200 3.3B outperforms all evaluated LLMs in the 7-8B parameter range across three out of the four language directions. While fine-tuning improves the performance of LLMs such as Mistral and Llama, these models still underperform compared to fine-tuned NLLB-200 3.3B models. Our findings highlight the ongoing need for specialized MT models to achieve high-quality domain-specific translation, especially in medium-resource and low-resource settings. Moreover, the superior performance of larger LLMs over their 8B variants suggests potential value in pre-training domain-specific medium-sized language models, employing targeted data selection and knowledge distillation approaches to enhance both quality and efficiency in specialized translation tasks.