# Classifier Enhanced Deep Learning Model for Erythroblast Differentiation with Limited Data

arXiv: https://arxiv.org/abs/2411.15592 · HTML: https://mlsanity.com/paper/2411.15592/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 24 references that are in the map.
- First posted on arXiv 23 Nov 2024.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [XGBoost: A Scalable Tree Boosting System](https://mlsanity.com/paper/1603.02754/) (2016)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [Understanding Random Forests: From Theory to Practice](https://mlsanity.com/paper/1407.7502/) (2014)
- [k-Nearest Neighbour Classifiers: 2nd Edition (with Python examples)](https://mlsanity.com/paper/2004.04523/) (2020)

## Abstract (arXiv)

Hematological disorders, which involve a variety of malignant conditions and genetic diseases affecting blood formation, present significant diagnostic challenges. One such major challenge in clinical settings is differentiating Erythroblast from WBCs. Our approach evaluates the efficacy of various machine learning (ML) classifiersunicodex2014SVM, XG-Boost, KNN, and Random Forestunicodex2014using the ResNet-50 deep learning model as a backbone in detecting and differentiating erythroblast blood smear images across training splits of different sizes. Our findings indicate that the ResNet50-SVM classifier consistently surpasses other models' overall test accuracy and erythroblast detection accuracy, maintaining high performance even with minimal training data. Even when trained on just 1% (168 images per class for eight classes) of the complete dataset, ML classifiers such as SVM achieved a test accuracy of 86.75% and an erythroblast precision of 98.9%, compared to 82.03% and 98.6% of pre-trained ResNet-50 models without any classifiers. When limited data is available, the proposed approach outperforms traditional deep learning models, thereby offering a solution for achieving higher classification accuracy for small and unique datasets, especially in resource-scarce settings.
