# Learning Modality-Aware Representations: Adaptive Group-wise Interaction Network for Multimodal MRI Synthesis

arXiv: https://arxiv.org/abs/2411.14684 · HTML: https://mlsanity.com/paper/2411.14684/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 34 of its 48 references that are in the map.
- First posted on arXiv 22 Nov 2024.

## Builds on (most cited first, 30 of 34)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Gaussian Error Linear Units (GELUs)](https://mlsanity.com/paper/1606.08415/) (2016)
- [Deformable Convolutional Networks](https://mlsanity.com/paper/1703.06211/) (2017)
- [ShuffleNet: An Extremely Efficient Convolutional Neural Network for Mobile Devices](https://mlsanity.com/paper/1707.01083/) (2017)
- [ShuffleNet V2: Practical Guidelines for Efficient CNN Architecture Design](https://mlsanity.com/paper/1807.11164/) (2018)
- [Deformable ConvNets v2: More Deformable, Better Results](https://mlsanity.com/paper/1811.11168/) (2018)
- [InternImage: Exploring Large-Scale Vision Foundation Models with Deformable Convolutions](https://mlsanity.com/paper/2211.05778/) (2022)
- [Plug-and-Play Image Restoration with Deep Denoiser Prior](https://mlsanity.com/paper/2008.13751/) (2020)
- [ResViT: Residual vision transformers for multi-modal medical image synthesis](https://mlsanity.com/paper/2106.16031/) (2021)
- [Image Synthesis in Multi-Contrast MRI with Conditional Generative Adversarial Networks](https://mlsanity.com/paper/1802.01221/) (2018)
- [Missing MRI Pulse Sequence Synthesis using Multi-Modal Generative Adversarial Network](https://mlsanity.com/paper/1904.12200/) (2019)
- [Hi-Net: Hybrid-fusion Network for Multi-modal MR Image Synthesis](https://mlsanity.com/paper/2002.05000/) (2020)
- [Dynamic Snake Convolution based on Topological Geometric Constraints for Tubular Structure Segmentation](https://mlsanity.com/paper/2307.08388/) (2023)
- [Deformable Kernel Networks for Joint Image Filtering](https://mlsanity.com/paper/1910.08373/) (2019)
- [CoreDiff: Contextual Error-Modulated Generalized Diffusion Model for Low-Dose CT Denoising and Generalization](https://mlsanity.com/paper/2304.01814/) (2023)
- [Adaptive Rotated Convolution for Rotated Object Detection](https://mlsanity.com/paper/2303.07820/) (2023)
- [Efficient Deformable ConvNets: Rethinking Dynamic and Sparse Operator for Vision Applications](https://mlsanity.com/paper/2401.06197/) (2024)
- [One Model to Synthesize Them All: Multi-contrast Multi-scale Transformer for Missing Data Imputation](https://mlsanity.com/paper/2204.13738/) (2022)
- [Unified Multi-Modal Image Synthesis for Missing Modality Imputation](https://mlsanity.com/paper/2304.05340/) (2023)
- [DiamondGAN: Unified Multi-Modal Generative Adversarial Networks for MRI Sequences Synthesis](https://mlsanity.com/paper/1904.12894/) (2019)
- [CollaGAN : Collaborative GAN for Missing Image Data Imputation](https://mlsanity.com/paper/1901.09764/) (2019)
- [Adversarial Synthesis Learning Enables Segmentation Without Target Modality Ground Truth](https://mlsanity.com/paper/1712.07695/) (2017)
- [Deformable Kernels: Adapting Effective Receptive Fields for Object Deformation](https://mlsanity.com/paper/1910.02940/) (2019)
- [Self-Consistent Recursive Diffusion Bridge for Medical Image Translation](https://mlsanity.com/paper/2405.06789/) (2024)
- [The Brain Tumor Segmentation (BraTS) Challenge 2023: Brain MR Image Synthesis for Tumor Segmentation (BraSyn)](https://mlsanity.com/paper/2305.09011/) (2023)
- [High-resolution medical image synthesis using progressively grown generative adversarial networks](https://mlsanity.com/paper/1805.03144/) (2018)
- [Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge](https://mlsanity.com/paper/2405.09787/) (2024)

## Built on by (most cited first, 4 of 4)

- [Virtual Full-stack Scanning of Brain MRI via Imputing Any Quantised Code](https://mlsanity.com/paper/2501.18328/) (2025)
- [MRI Cross-Modal Synthesis: A Comparative Study of Generative Models for T1-to-T2 Reconstruction](https://mlsanity.com/paper/2602.07068/) (2026)
- [Exploiting Completeness Perception with Diffusion Transformer for Unified 3D MRI Synthesis](https://mlsanity.com/paper/2602.18400/) (2026)
- [Learning Where and What to Lift for Bi-planar X-ray-to-CT Reconstruction](https://mlsanity.com/paper/2608.17255/) (2026)

## Abstract (arXiv)

Multimodal MR image synthesis aims to generate missing modality images by effectively fusing and mapping from a subset of available MRI modalities. Most existing methods adopt an image-to-image translation paradigm, treating multiple modalities as input channels. However, these approaches often yield sub-optimal results due to the inherent difficulty in achieving precise feature- or semantic-level alignment across modalities. To address these challenges, we propose an Adaptive Group-wise Interaction Network (AGI-Net) that explicitly models both inter-modality and intra-modality relationships for multimodal MR image synthesis. Specifically, feature channels are first partitioned into predefined groups, after which an adaptive rolling mechanism is applied to conventional convolutional kernels to better capture feature and semantic correspondences between different modalities. In parallel, a cross-group attention module is introduced to enable effective feature fusion across groups, thereby enhancing the network's representational capacity. We validate the proposed AGI-Net on the publicly available IXI and BraTS2023 datasets. Experimental results demonstrate that AGI-Net achieves state-of-the-art performance in multimodal MR image synthesis tasks, confirming the effectiveness of its modality-aware interaction design. We release the relevant code at: https://github.com/zunzhumu/Adaptive-Group-wise-Interaction-Network-for-Multimodal-MRI-Synthesis.git.