# Look a Group at Once: Multi-Slide Modeling for Survival Prediction

arXiv: https://arxiv.org/abs/2411.11487 · HTML: https://mlsanity.com/paper/2411.11487/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 7 of its 45 references that are in the map.
- First posted on arXiv 18 Nov 2024.

## Builds on (most cited first, 7 of 7)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [Gaussian Error Linear Units (GELUs)](https://mlsanity.com/paper/1606.08415/) (2016)
- [Searching for Activation Functions](https://mlsanity.com/paper/1710.05941/) (2017)
- [MambaMIL: Enhancing Long Sequence Modeling with Sequence Reordering in Computational Pathology](https://mlsanity.com/paper/2403.06800/) (2024)
- [AMIGO: Sparse Multi-Modal Graph Transformer with Shared-Context Processing for Representation Learning of Giga-pixel Images](https://mlsanity.com/paper/2303.00865/) (2023)

## Built on by (most cited first, 1 of 1)

- [Efficient AI-Driven Multi-Section Whole Slide Image Analysis for Biochemical Recurrence Prediction in Prostate Cancer](https://mlsanity.com/paper/2603.20273/) (2026)

## Abstract (arXiv)

Survival prediction is a critical task in pathology. In clinical practice, pathologists often examine multiple cases, leveraging a broader spectrum of cancer phenotypes to enhance pathological assessment. Despite significant advancements in deep learning, current solutions typically model each slide as a sample, struggling to effectively capture comparable and slide-agnostic pathological features. In this paper, we introduce GroupMIL, a novel framework inspired by the clinical practice of collective analysis, which models multiple slides as a single sample and organizes groups of patches and slides sequentially to capture cross-slide prognostic features. We also present GPAMamba, a model designed to facilitate intra- and inter-slide feature interactions, effectively capturing local micro-environmental characteristics within slide-level graphs while uncovering essential prognostic patterns across an extended patch sequence within the group framework. Furthermore, we develop a dual-head predictor that delivers comprehensive survival risk and probability assessments for each patient. Extensive empirical evaluations demonstrate that our model significantly outperforms state-of-the-art approaches across five datasets from The Cancer Genome Atlas.