# Video Denoising in Fluorescence Guided Surgery

arXiv: https://arxiv.org/abs/2411.09798 · HTML: https://mlsanity.com/paper/2411.09798/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 39 of its 65 references that are in the map.
- First posted on arXiv 14 Nov 2024.

## Builds on (most cited first, 30 of 39)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Layer Normalization](https://mlsanity.com/paper/1607.06450/) (2016)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [Restormer: Efficient Transformer for High-Resolution Image Restoration](https://mlsanity.com/paper/2111.09881/) (2021)
- [Deformable Convolutional Networks](https://mlsanity.com/paper/1703.06211/) (2017)
- [The 2017 DAVIS Challenge on Video Object Segmentation](https://mlsanity.com/paper/1704.00675/) (2017)
- [Uformer: A General U-Shaped Transformer for Image Restoration](https://mlsanity.com/paper/2106.03106/) (2021)
- [Multi-Stage Progressive Image Restoration](https://mlsanity.com/paper/2102.02808/) (2021)
- [Simple Baselines for Image Restoration](https://mlsanity.com/paper/2204.04676/) (2022)
- [Deformable ConvNets v2: More Deformable, Better Results](https://mlsanity.com/paper/1811.11168/) (2018)
- [Noise2Noise: Learning Image Restoration without Clean Data](https://mlsanity.com/paper/1803.04189/) (2018)
- [EDVR: Video Restoration with Enhanced Deformable Convolutional Networks](https://mlsanity.com/paper/1905.02716/) (2019)
- [Deep Laplacian Pyramid Networks for Fast and Accurate Super-Resolution](https://mlsanity.com/paper/1704.03915/) (2017)
- [Noise2Void - Learning Denoising from Single Noisy Images](https://mlsanity.com/paper/1811.10980/) (2018)
- [BasicVSR++: Improving Video Super-Resolution with Enhanced Propagation and Alignment](https://mlsanity.com/paper/2104.13371/) (2021)
- [Learning Enriched Features for Real Image Restoration and Enhancement](https://mlsanity.com/paper/2003.06792/) (2020)
- [BasicVSR: The Search for Essential Components in Video Super-Resolution and Beyond](https://mlsanity.com/paper/2012.02181/) (2020)
- [MAXIM: Multi-Axis MLP for Image Processing](https://mlsanity.com/paper/2201.02973/) (2022)
- [Noise2Self: Blind Denoising by Self-Supervision](https://mlsanity.com/paper/1901.11365/) (2019)
- [HINet: Half Instance Normalization Network for Image Restoration](https://mlsanity.com/paper/2105.06086/) (2021)
- [A Physics-based Noise Formation Model for Extreme Low-light Raw Denoising](https://mlsanity.com/paper/2003.12751/) (2020)
- [FastDVDnet: Towards Real-Time Deep Video Denoising Without Flow Estimation](https://mlsanity.com/paper/1907.01361/) (2019)
- [Understanding Deformable Alignment in Video Super-Resolution](https://mlsanity.com/paper/2009.07265/) (2020)
- [Supervised Raw Video Denoising with a Benchmark Dataset on Dynamic Scenes](https://mlsanity.com/paper/2003.14013/) (2020)
- [NBNet: Noise Basis Learning for Image Denoising with Subspace Projection](https://mlsanity.com/paper/2012.15028/) (2020)
- [Rethinking Noise Synthesis and Modeling in Raw Denoising](https://mlsanity.com/paper/2110.04756/) (2021)
- [DVDnet: A Fast Network for Deep Video Denoising](https://mlsanity.com/paper/1906.11890/) (2019)

## Abstract (arXiv)

Fluorescence guided surgery (FGS) is a promising surgical technique that gives surgeons a unique view of tissue that is used to guide their practice by delineating tissue types and diseased areas. As new fluorescent contrast agents are developed that have low fluorescent photon yields, it becomes increasingly important to develop computational models to allow FGS systems to maintain good video quality in real time environments. To further complicate this task, FGS has a difficult bias noise term from laser leakage light (LLL) that represents unfiltered excitation light that can be on the order of the fluorescent signal. Most conventional video denoising methods focus on zero mean noise, and non-causal processing, both of which are violated in FGS. Luckily in FGS, often a co-located reference video is also captured which we use to simulate the LLL and assist in the denoising processes. In this work, we propose an accurate noise simulation pipeline that includes LLL and propose three baseline deep learning based algorithms for FGS video denoising.