# GAN-Based Architecture for Low-dose Computed Tomography Imaging Denoising

arXiv: https://arxiv.org/abs/2411.09512 · HTML: https://mlsanity.com/paper/2411.09512/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 28 references that are in the map.
- First posted on arXiv 14 Nov 2024.

## Builds on (most cited first, 9 of 9)

- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [Progressive Growing of GANs for Improved Quality, Stability, and Variation](https://mlsanity.com/paper/1710.10196/) (2017)
- [Conditional Generative Adversarial Nets](https://mlsanity.com/paper/1411.1784/) (2014)
- [Photo-Realistic Single Image Super-Resolution Using a Generative Adversarial Network](https://mlsanity.com/paper/1609.04802/) (2016)
- [Generative Adversarial Networks: An Overview](https://mlsanity.com/paper/1710.07035/) (2017)
- [DualGAN: Unsupervised Dual Learning for Image-to-Image Translation](https://mlsanity.com/paper/1704.02510/) (2017)
- [DU-GAN: Generative Adversarial Networks with Dual-Domain U-Net Based Discriminators for Low-Dose CT Denoising](https://mlsanity.com/paper/2108.10772/) (2021)
- [Sharpness-aware Low dose CT denoising using conditional generative adversarial network](https://mlsanity.com/paper/1708.06453/) (2017)

## Abstract (arXiv)

Generative Adversarial Networks (GANs) have surfaced as a revolutionary element within the domain of low-dose computed tomography (LDCT) imaging, providing an advanced resolution to the enduring issue of reconciling radiation exposure with image quality. This comprehensive review synthesizes the rapid advancements in GAN-based LDCT denoising techniques, examining the evolution from foundational architectures to state-of-the-art models incorporating advanced features such as anatomical priors, perceptual loss functions, and innovative regularization strategies. We critically analyze various GAN architectures, including conditional GANs (cGANs), CycleGANs, and Super-Resolution GANs (SRGANs), elucidating their unique strengths and limitations in the context of LDCT denoising. The evaluation provides both qualitative and quantitative results related to the improvements in performance in benchmark and clinical datasets with metrics such as PSNR, SSIM, and LPIPS. After highlighting the positive results, we discuss some of the challenges preventing a wider clinical use, including the interpretability of the images generated by GANs, synthetic artifacts, and the need for clinically relevant metrics. The review concludes by highlighting the essential significance of GAN-based methodologies in the progression of precision medicine via tailored LDCT denoising models, underlining the transformative possibilities presented by artificial intelligence within contemporary radiological practice.