# MedINST: Meta Dataset of Biomedical Instructions

arXiv: https://arxiv.org/abs/2410.13458 · HTML: https://mlsanity.com/paper/2410.13458/

## Key facts

- Cited by 7 papers in the map (data through 14 Oct 2026).
- Builds on 32 of its 61 references that are in the map.
- First posted on arXiv 17 Oct 2024.

## Builds on (most cited first, 30 of 32)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Finetuned Language Models Are Zero-Shot Learners](https://mlsanity.com/paper/2109.01652/) (2021)
- [Self-Instruct: Aligning Language Models with Self-Generated Instructions](https://mlsanity.com/paper/2212.10560/) (2022)
- [Pre-train, Prompt, and Predict: A Systematic Survey of Prompting Methods in Natural Language Processing](https://mlsanity.com/paper/2107.13586/) (2021)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [FEVER: a large-scale dataset for Fact Extraction and VERification](https://mlsanity.com/paper/1803.05355/) (2018)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [Super-NaturalInstructions: Generalization via Declarative Instructions on 1600+ NLP Tasks](https://mlsanity.com/paper/2204.07705/) (2022)
- [The Flan Collection: Designing Data and Methods for Effective Instruction Tuning](https://mlsanity.com/paper/2301.13688/) (2023)
- [Fact or Fiction: Verifying Scientific Claims](https://mlsanity.com/paper/2004.14974/) (2020)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [Transfer Learning in Biomedical Natural Language Processing: An Evaluation of BERT and ELMo on Ten Benchmarking Datasets](https://mlsanity.com/paper/1906.05474/) (2019)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [Explainable Automated Fact-Checking for Public Health Claims](https://mlsanity.com/paper/2010.09926/) (2020)
- [Large Language Models are Few-Shot Clinical Information Extractors](https://mlsanity.com/paper/2205.12689/) (2022)
- [MedDialog: Two Large-scale Medical Dialogue Datasets](https://mlsanity.com/paper/2004.03329/) (2020)
- [Structural Scaffolds for Citation Intent Classification in Scientific Publications](https://mlsanity.com/paper/1904.01608/) (2019)
- [SciFive: a text-to-text transformer model for biomedical literature](https://mlsanity.com/paper/2106.03598/) (2021)
- [Multi-XScience: A Large-scale Dataset for Extreme Multi-document Summarization of Scientific Articles](https://mlsanity.com/paper/2010.14235/) (2020)
- [AlpaCare:Instruction-tuned Large Language Models for Medical Application](https://mlsanity.com/paper/2310.14558/) (2023)
- [PMC-LLaMA: Towards Building Open-source Language Models for Medicine](https://mlsanity.com/paper/2304.14454/) (2023)
- [Pre-trained Language Models in Biomedical Domain: A Systematic Survey](https://mlsanity.com/paper/2110.05006/) (2021)
- [MedMentions: A Large Biomedical Corpus Annotated with UMLS Concepts](https://mlsanity.com/paper/1902.09476/) (2019)
- [Effective Transfer Learning for Identifying Similar Questions: Matching User Questions to COVID-19 FAQs](https://mlsanity.com/paper/2008.13546/) (2020)
- [Clinical XLNet: Modeling Sequential Clinical Notes and Predicting Prolonged Mechanical Ventilation](https://mlsanity.com/paper/1912.11975/) (2019)
- [MeDAL: Medical Abbreviation Disambiguation Dataset for Natural Language Understanding Pretraining](https://mlsanity.com/paper/2012.13978/) (2020)

## Built on by (most cited first, 7 of 7)

- [ManipLVM-R1: Reinforcement Learning for Reasoning in Embodied Manipulation with Large Vision-Language Models](https://mlsanity.com/paper/2505.16517/) (2025)
- [Audio Jailbreak: An Open Comprehensive Benchmark for Jailbreaking Large Audio-Language Models](https://mlsanity.com/paper/2505.15406/) (2025)
- [PhantomBench: Benchmarking the Non-existential Threat of Language Models](https://mlsanity.com/paper/2606.11105/) (2026)
- [MedPath: Multi-Domain Cross-Vocabulary Hierarchical Paths for Biomedical Entity Linking](https://mlsanity.com/paper/2511.10887/) (2025)
- [Toward Federated Large Language Models in Medicine: A Parameter-Efficient Framework for Privacy-Preserving, Multi-Institutional Adaptation](https://mlsanity.com/paper/2601.22124/) (2026)
- [On the Utility and Factual Reliability of Pruned Mixture-of-Experts Models in the Biomedical Domain](https://mlsanity.com/paper/2607.01444/) (2026)
- [A Dataset of Robot-Patient and Doctor-Patient Medical Dialogues for Spoken Language Processing Tasks](https://mlsanity.com/paper/2605.26747/) (2026)

## Abstract (arXiv)

The integration of large language model (LLM) techniques in the field of medical analysis has brought about significant advancements, yet the scarcity of large, diverse, and well-annotated datasets remains a major challenge. Medical data and tasks, which vary in format, size, and other parameters, require extensive preprocessing and standardization for effective use in training LLMs. To address these challenges, we introduce MedINST, the Meta Dataset of Biomedical Instructions, a novel multi-domain, multi-task instructional meta-dataset. MedINST comprises 133 biomedical NLP tasks and over 7 million training samples, making it the most comprehensive biomedical instruction dataset to date. Using MedINST as the meta dataset, we curate MedINST32, a challenging benchmark with different task difficulties aiming to evaluate LLMs' generalization ability. We fine-tune several LLMs on MedINST and evaluate on MedINST32, showcasing enhanced cross-task generalization.