# Fool Me Once? Contrasting Textual and Visual Explanations in a Clinical Decision-Support Setting

arXiv: https://arxiv.org/abs/2410.12284 · HTML: https://mlsanity.com/paper/2410.12284/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Builds on 39 of its 74 references that are in the map.
- First posted on arXiv 16 Oct 2024.

## Builds on (most cited first, 30 of 39)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [Sanity Checks for Saliency Maps](https://mlsanity.com/paper/1810.03292/) (2018)
- [Concept Bottleneck Models](https://mlsanity.com/paper/2007.04612/) (2020)
- [Multimodal Chain-of-Thought Reasoning in Language Models](https://mlsanity.com/paper/2302.00923/) (2023)
- [Measuring Faithfulness in Chain-of-Thought Reasoning](https://mlsanity.com/paper/2307.13702/) (2023)
- [Towards Faithfully Interpretable NLP Systems: How should we define and evaluate faithfulness?](https://mlsanity.com/paper/2004.03685/) (2020)
- [e-SNLI: Natural Language Inference with Natural Language Explanations](https://mlsanity.com/paper/1812.01193/) (2018)
- [Measuring Association Between Labels and Free-Text Rationales](https://mlsanity.com/paper/2010.12762/) (2020)
- [Generating Visual Explanations](https://mlsanity.com/paper/1603.08507/) (2016)
- [WT5?! Training Text-to-Text Models to Explain their Predictions](https://mlsanity.com/paper/2004.14546/) (2020)
- [Debugging Tests for Model Explanations](https://mlsanity.com/paper/2011.05429/) (2020)
- [What Clinicians Want: Contextualizing Explainable Machine Learning for Clinical End Use](https://mlsanity.com/paper/1905.05134/) (2019)
- [Human-Centered Explainable AI (XAI): From Algorithms to User Experiences](https://mlsanity.com/paper/2110.10790/) (2021)
- [Do Concept Bottleneck Models Learn as Intended?](https://mlsanity.com/paper/2105.04289/) (2021)
- [Faithfulness Tests for Natural Language Explanations](https://mlsanity.com/paper/2305.18029/) (2023)
- [HIVE: Evaluating the Human Interpretability of Visual Explanations](https://mlsanity.com/paper/2112.03184/) (2021)
- [What I Cannot Predict, I Do Not Understand: A Human-Centered Evaluation Framework for Explainability Methods](https://mlsanity.com/paper/2112.04417/) (2021)
- [Optimizing the Factual Correctness of a Summary: A Study of Summarizing Radiology Reports](https://mlsanity.com/paper/1911.02541/) (2019)
- [Leakage-Adjusted Simulatability: Can Models Generate Non-Trivial Explanations of Their Behavior in Natural Language?](https://mlsanity.com/paper/2010.04119/) (2020)
- [Human-centered Explainable AI: Towards a Reflective Sociotechnical Approach](https://mlsanity.com/paper/2002.01092/) (2020)
- [Evaluating Saliency Map Explanations for Convolutional Neural Networks: A User Study](https://mlsanity.com/paper/2002.00772/) (2020)
- [e-ViL: A Dataset and Benchmark for Natural Language Explanations in Vision-Language Tasks](https://mlsanity.com/paper/2105.03761/) (2021)
- [A Vision-Language Foundation Model to Enhance Efficiency of Chest X-ray Interpretation](https://mlsanity.com/paper/2401.12208/) (2024)
- [This Looks Like That... Does it? Shortcomings of Latent Space Prototype Interpretability in Deep Networks](https://mlsanity.com/paper/2105.02968/) (2021)
- [Connecting Algorithmic Research and Usage Contexts: A Perspective of Contextualized Evaluation for Explainable AI](https://mlsanity.com/paper/2206.10847/) (2022)
- [How Useful Are the Machine-Generated Interpretations to General Users? A Human Evaluation on Guessing the Incorrectly Predicted Labels](https://mlsanity.com/paper/2008.11721/) (2020)
- [Are Visual Explanations Useful? A Case Study in Model-in-the-Loop Prediction](https://mlsanity.com/paper/2007.12248/) (2020)

## Built on by (most cited first, 5 of 5)

- [A Necessary Step toward Faithfulness: Measuring and Improving Consistency in Free-Text Explanations](https://mlsanity.com/paper/2505.19299/) (2025)
- [A Taxonomy for Design and Evaluation of Prompt-Based Natural Language Explanations](https://mlsanity.com/paper/2507.10585/) (2025)
- [AI Chaperones Are (Really) All You Need to Prevent Parasocial Relationships with Chatbots](https://mlsanity.com/paper/2508.15748/) (2025)
- [NeuroFaith: Evaluating LLM Self-Explanation Faithfulness via Internal Representation Alignment](https://mlsanity.com/paper/2506.09277/) (2025)
- [Explainable Melanoma Diagnosis with Contrastive Learning and LLM-based Report Generation](https://mlsanity.com/paper/2512.06105/) (2025)

## Abstract (arXiv)

The growing capabilities of AI models are leading to their wider use, including in safety-critical domains. Explainable AI (XAI) aims to make these models safer to use by making their inference process more transparent. However, current explainability methods are seldom evaluated in the way they are intended to be used: by real-world end users. To address this, we conducted a large-scale user study with 85 healthcare practitioners in the context of human-AI collaborative chest X-ray analysis. We evaluated three types of explanations: visual explanations (saliency maps), natural language explanations, and a combination of both modalities. We specifically examined how different explanation types influence users depending on whether the AI advice and explanations are factually correct. We find that text-based explanations lead to significant over-reliance, which is alleviated by combining them with saliency maps. We also observe that the quality of explanations, that is, how much factually correct information they entail, and how much this aligns with AI correctness, significantly impacts the usefulness of the different explanation types.
