# Visual Fixation-Based Retinal Prosthetic Simulation

arXiv: https://arxiv.org/abs/2410.11688 · HTML: https://mlsanity.com/paper/2410.11688/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 12 of its 25 references that are in the map.
- First posted on arXiv 15 Oct 2024.

## Builds on (most cited first, 12 of 12)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Emerging Properties in Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.14294/) (2021)
- [Predicting Human Eye Fixations via an LSTM-based Saliency Attentive Model](https://mlsanity.com/paper/1611.09571/) (2016)
- [Hybrid Neural Autoencoders for Stimulus Encoding in Visual and Other Sensory Neuroprostheses](https://mlsanity.com/paper/2205.13623/) (2022)
- [Human-in-the-Loop Optimization for Deep Stimulus Encoding in Visual Prostheses](https://mlsanity.com/paper/2306.13104/) (2023)
- [Deep Learning-Based Perceptual Stimulus Encoder for Bionic Vision](https://mlsanity.com/paper/2203.05604/) (2022)
- [A Deep Learning-based in silico Framework for Optimization on Retinal Prosthetic Stimulation](https://mlsanity.com/paper/2302.03570/) (2023)
- [Optimizing Retinal Prosthetic Stimuli with Conditional Invertible Neural Networks](https://mlsanity.com/paper/2403.04884/) (2024)

## Abstract (arXiv)

This study proposes a retinal prosthetic simulation framework driven by visual fixations, inspired by the saccade mechanism, and assesses performance improvements through end-to-end optimization in a classification task. Salient patches are predicted from input images using the self-attention map of a vision transformer to mimic visual fixations. These patches are then encoded by a trainable U-Net and simulated using the pulse2percept framework to predict visual percepts. By incorporating a learnable encoder, we aim to optimize the visual information transmitted to the retinal implant, addressing both the limited resolution of the electrode array and the distortion between the input stimuli and resulting phosphenes. The predicted percepts are evaluated using the self-supervised DINOv2 foundation model, with an optional learnable linear layer for classification accuracy. On a subset of the ImageNet validation set, the fixation-based framework achieves a classification accuracy of 87.72%, using computational parameters based on a real subject's physiological data, significantly outperforming the downsampling-based accuracy of 40.59% and approaching the healthy upper bound of 92.76%. Our approach shows promising potential for producing more semantically understandable percepts with the limited resolution available in retinal prosthetics.