# Balancing Continuous Pre-Training and Instruction Fine-Tuning: Optimizing Instruction-Following in LLMs

arXiv: https://arxiv.org/abs/2410.10739 · HTML: https://mlsanity.com/paper/2410.10739/

## Key facts

- Cited by 12 papers in the map (data through 14 Oct 2026).
- Builds on 26 of its 43 references that are in the map.
- First posted on arXiv 14 Oct 2024.

## Builds on (most cited first, 26 of 26)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Training Verifiers to Solve Math Word Problems](https://mlsanity.com/paper/2110.14168/) (2021)
- [Direct Preference Optimization: Your Language Model is Secretly a Reward Model](https://mlsanity.com/paper/2305.18290/) (2023)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Think you have Solved Question Answering? Try ARC, the AI2 Reasoning Challenge](https://mlsanity.com/paper/1803.05457/) (2018)
- [HellaSwag: Can a Machine Really Finish Your Sentence?](https://mlsanity.com/paper/1905.07830/) (2019)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [TruthfulQA: Measuring How Models Mimic Human Falsehoods](https://mlsanity.com/paper/2109.07958/) (2021)
- [PIQA: Reasoning about Physical Commonsense in Natural Language](https://mlsanity.com/paper/1911.11641/) (2019)
- [The Pile: An 800GB Dataset of Diverse Text for Language Modeling](https://mlsanity.com/paper/2101.00027/) (2020)
- [Code Llama: Open Foundation Models for Code](https://mlsanity.com/paper/2308.12950/) (2023)
- [BLOOM: A 176B-Parameter Open-Access Multilingual Language Model](https://mlsanity.com/paper/2211.05100/) (2022)
- [MMLU-Pro: A More Robust and Challenging Multi-Task Language Understanding Benchmark](https://mlsanity.com/paper/2406.01574/) (2024)
- [WizardLM: Empowering large pre-trained language models to follow complex instructions](https://mlsanity.com/paper/2304.12244/) (2023)
- [Super-NaturalInstructions: Generalization via Declarative Instructions on 1600+ NLP Tasks](https://mlsanity.com/paper/2204.07705/) (2022)
- [DoRA: Weight-Decomposed Low-Rank Adaptation](https://mlsanity.com/paper/2402.09353/) (2024)
- [Language Models are Super Mario: Absorbing Abilities from Homologous Models as a Free Lunch](https://mlsanity.com/paper/2311.03099/) (2023)
- [Principle-Driven Self-Alignment of Language Models from Scratch with Minimal Human Supervision](https://mlsanity.com/paper/2305.03047/) (2023)
- [Model Breadcrumbs: Scaling Multi-Task Model Merging with Sparse Masks](https://mlsanity.com/paper/2312.06795/) (2023)
- [Online Fast Adaptation and Knowledge Accumulation: a New Approach to Continual Learning](https://mlsanity.com/paper/2003.05856/) (2020)
- [PLLaMa: An Open-source Large Language Model for Plant Science](https://mlsanity.com/paper/2401.01600/) (2024)
- [Low-rank Adaptation of Large Language Model Rescoring for Parameter-Efficient Speech Recognition](https://mlsanity.com/paper/2309.15223/) (2023)
- [Fundus: A Simple-to-Use News Scraper Optimized for High Quality Extractions](https://mlsanity.com/paper/2403.15279/) (2024)

## Built on by (most cited first, 12 of 12)

- [Beyond Static Models: An Evolving Framework for Continual Learning in Large Language Models across Training Stages](https://mlsanity.com/paper/2603.12658/) (2026)
- [Is Extending Modality The Right Path Towards Omni-Modality?](https://mlsanity.com/paper/2506.01872/) (2025)
- [LoRAFusion: Efficient LoRA Fine-Tuning for LLMs](https://mlsanity.com/paper/2510.00206/) (2025)
- [Thomson: Continual Learning of Frontier Models for SovereignAI](https://mlsanity.com/paper/2608.27147/) (2026)
- [Mortgage Language Model: Domain-Adaptive Pretraining with Residual Instruction, Alignment Tuning, and Task-Specific Routing](https://mlsanity.com/paper/2511.21101/) (2025)
- [Can Continual Pre-training Bridge the Performance Gap between General-purpose and Specialized Language Models in the Medical Domain?](https://mlsanity.com/paper/2604.19394/) (2026)
- [SLAI T-Rex: Full-Parameter Post-training of the DeepSeek-V4 Family on Ascend SuperPOD](https://mlsanity.com/paper/2607.20145/) (2026)
- [Uncovering Scaling Laws for Large Language Models via Inverse Problems](https://mlsanity.com/paper/2509.07909/) (2025)
- [From Slides to Chatbots: Enhancing Large Language Models with University Course Materials](https://mlsanity.com/paper/2510.22272/) (2025)
- [Retrievable Gradients: Continual Post-Training Without Cumulative Weight Drift](https://mlsanity.com/paper/2606.15734/) (2026)
- [Reward-Free Code Alignment from Pretrained or Fine-Tuned LLM: Unpacking the Trade-offs for Code Generation](https://mlsanity.com/paper/2606.28998/) (2026)
- [Reading the News: Adapting Large Language Models to Swedish Journalism Through Continued Pre-Training](https://mlsanity.com/paper/2608.30609/) (2026)

## Abstract (arXiv)

Large Language Models (LLMs) for public use require continuous pre-training to remain up-to-date with the latest data. The models also need to be fine-tuned with specific instructions to maintain their ability to follow instructions accurately. Typically, LLMs are released in two versions: the Base LLM, pre-trained on diverse data, and the instruction-refined LLM, additionally trained with specific instructions for better instruction following. The question arises as to which model should undergo continuous pre-training to maintain its instruction-following abilities while also staying current with the latest data. In this study, we delve into the intricate relationship between continuous pre-training and instruction fine-tuning of the LLMs and investigate the impact of continuous pre-training on the instruction following abilities of both the base and its instruction finetuned model. Further, the instruction fine-tuning process is computationally intense and requires a substantial number of hand-annotated examples for the model to learn effectively. This study aims to find the most compute-efficient strategy to gain up-to-date knowledge and instruction-following capabilities without requiring any instruction data and fine-tuning. We empirically prove our findings on the LLaMa 3, 3.1 and Qwen 2, 2.5 family of base and instruction models, providing a comprehensive exploration of our hypotheses across varying sizes of pre-training data corpus and different LLMs settings.
