# Manifold-Aware Local Feature Modeling for Semi-Supervised Medical Image Segmentation

arXiv: https://arxiv.org/abs/2410.10287 · HTML: https://mlsanity.com/paper/2410.10287/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 34 of its 55 references that are in the map.
- First posted on arXiv 14 Oct 2024.

## Builds on (most cited first, 30 of 34)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [MixMatch: A Holistic Approach to Semi-Supervised Learning](https://mlsanity.com/paper/1905.02249/) (2019)
- [Self-training with Noisy Student improves ImageNet classification](https://mlsanity.com/paper/1911.04252/) (2019)
- [Temporal Ensembling for Semi-Supervised Learning](https://mlsanity.com/paper/1610.02242/) (2016)
- [Virtual Adversarial Training: A Regularization Method for Supervised and Semi-Supervised Learning](https://mlsanity.com/paper/1704.03976/) (2017)
- [Accelerating 3D Deep Learning with PyTorch3D](https://mlsanity.com/paper/2007.08501/) (2020)
- [Generalised Dice overlap as a deep learning loss function for highly unbalanced segmentations](https://mlsanity.com/paper/1707.03237/) (2017)
- [Point Transformer V3: Simpler, Faster, Stronger](https://mlsanity.com/paper/2312.10035/) (2023)
- [Vision Transformer Adapter for Dense Predictions](https://mlsanity.com/paper/2205.08534/) (2022)
- [An Introduction to Convolutional Neural Networks](https://mlsanity.com/paper/1511.08458/) (2015)
- [Semi-Supervised Semantic Segmentation with Cross Pseudo Supervision](https://mlsanity.com/paper/2106.01226/) (2021)
- [Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentation](https://mlsanity.com/paper/1907.07034/) (2019)
- [Semi-Supervised Semantic Segmentation with Cross-Consistency Training](https://mlsanity.com/paper/2003.09005/) (2020)
- [In Defense of Pseudo-Labeling: An Uncertainty-Aware Pseudo-label Selection Framework for Semi-Supervised Learning](https://mlsanity.com/paper/2101.06329/) (2021)
- [Semi-Supervised Semantic Segmentation Using Unreliable Pseudo-Labels](https://mlsanity.com/paper/2203.03884/) (2022)
- [Semi-supervised Medical Image Segmentation through Dual-task Consistency](https://mlsanity.com/paper/2009.04448/) (2020)
- [DeepOrgan: Multi-level Deep Convolutional Networks for Automated Pancreas Segmentation](https://mlsanity.com/paper/1506.06448/) (2015)
- [Shape-aware Semi-supervised 3D Semantic Segmentation for Medical Images](https://mlsanity.com/paper/2007.10732/) (2020)
- [Transformation Consistent Self-ensembling Model for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/1903.00348/) (2019)
- [Bidirectional Copy-Paste for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2305.00673/) (2023)
- [UNETR++: Delving into Efficient and Accurate 3D Medical Image Segmentation](https://mlsanity.com/paper/2212.04497/) (2022)
- [Exploring Smoothness and Class-Separation for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2203.01324/) (2022)
- [ShapeConv: Shape-aware Convolutional Layer for Indoor RGB-D Semantic Segmentation](https://mlsanity.com/paper/2108.10528/) (2021)
- [Inconsistency-aware Uncertainty Estimation for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2110.08762/) (2021)
- [Semantic Image Segmentation with Task-Specific Edge Detection Using CNNs and a Discriminatively Trained Domain Transform](https://mlsanity.com/paper/1511.03328/) (2015)
- [UCC: Uncertainty guided Cross-head Co-training for Semi-Supervised Semantic Segmentation](https://mlsanity.com/paper/2205.10334/) (2022)
- [Classification With an Edge: Improving Semantic Image Segmentation with Boundary Detection](https://mlsanity.com/paper/1612.01337/) (2016)

## Built on by (most cited first, 1 of 1)

- [CheXLearner: Text-Guided Fine-Grained Representation Learning for Progression Detection](https://mlsanity.com/paper/2505.06903/) (2025)

## Abstract (arXiv)

Achieving precise medical image segmentation is vital for effective treatment planning and accurate disease diagnosis. Traditional fully-supervised deep learning methods, though highly precise, are heavily reliant on large volumes of labeled data, which are often difficult to obtain due to the expertise required for medical annotations. This has led to the rise of semi-supervised learning approaches that utilize both labeled and unlabeled data to mitigate the label scarcity issue. In this paper, we introduce the Manifold-Aware Local Feature Modeling Network (MANet), which enhances the U-Net architecture by incorporating manifold supervision signals. This approach focuses on improving boundary accuracy, which is crucial for reliable medical diagnosis. To further extend the versatility of our method, we propose two variants: MA-Sobel and MA-Canny. The MA-Sobel variant employs the Sobel operator, which is effective for both 2D and 3D data, while the MA-Canny variant utilizes the Canny operator, specifically designed for 2D images, to refine boundary detection. These variants allow our method to adapt to various medical image modalities and dimensionalities, ensuring broader applicability. Our extensive experiments on datasets such as ACDC, LA, and Pancreas-NIH demonstrate that MANet consistently surpasses state-of-the-art methods in performance metrics like Dice and Jaccard scores. The proposed method also shows improved generalization across various semi-supervised segmentation networks, highlighting its robustness and effectiveness. Visual analysis of segmentation results confirms that MANet offers clearer and more accurate class boundaries, underscoring the value of manifold information in medical image segmentation.