# Adaptive Reasoning and Acting in Medical Language Agents

arXiv: https://arxiv.org/abs/2410.10020 · HTML: https://mlsanity.com/paper/2410.10020/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 5 of its 8 references that are in the map.
- First posted on arXiv 13 Oct 2024.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)
- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 5 of 5)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [Large Language Models: A Survey](https://mlsanity.com/paper/2402.06196/) (2024)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)

## Built on by (most cited first, 9 of 9)

- [A Survey of LLM-based Agents in Medicine: How far are we from Baymax?](https://mlsanity.com/paper/2502.11211/) (2025)
- [A Survey of Agentic Reasoning for Large Language Models: Towards Recursively Self-Improving and Collective Agents](https://mlsanity.com/paper/2601.12538/) (2026)
- [ReasonMed: A 370K Multi-Agent Generated Dataset for Advancing Medical Reasoning](https://mlsanity.com/paper/2506.09513/) (2025)
- [MedSentry: Understanding and Mitigating Safety Risks in Medical LLM Multi-Agent Systems](https://mlsanity.com/paper/2505.20824/) (2025)
- [AUTOCT: Automating Interpretable Clinical Trial Prediction with LLM Agents](https://mlsanity.com/paper/2506.04293/) (2025)
- [Generative AI for Healthcare: Fundamentals, Challenges, and Perspectives](https://mlsanity.com/paper/2510.24551/) (2025)
- [Knowledge-Augmented Long-CoT Generation for Complex Biomolecular Reasoning](https://mlsanity.com/paper/2511.08024/) (2025)
- [Surgical AI Copilot: Energy-Based Fourier Gradient Low-Rank Adaptation for Surgical LLM Agent Reasoning and Planning](https://mlsanity.com/paper/2503.09474/) (2025)
- [Modeling Clinical Concern Trajectories in Language Model Agents](https://mlsanity.com/paper/2604.27872/) (2026)

## Abstract (arXiv)

This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to iteratively refine their reasoning and actions following incorrect diagnoses, fostering improved decision-making over time. Experiments show that the implementation of the adaptive LLM-based doctor agents achieve correct diagnoses through dynamic interactions with simulated patients. The evaluations highlight the capacity of autonomous agents to adapt and improve in complex medical scenarios. Future enhancements will focus on refining the algorithm and expanding its applicability across a wider range of tasks and different large language models.