# Repurposing Foundation Model for Generalizable Medical Time Series Classification

arXiv: https://arxiv.org/abs/2410.03794 · HTML: https://mlsanity.com/paper/2410.03794/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 34 of its 63 references that are in the map.
- First posted on arXiv 3 Oct 2024.

## Builds on (most cited first, 30 of 34)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Learning to Prompt for Vision-Language Models](https://mlsanity.com/paper/2109.01134/) (2021)
- [Informer: Beyond Efficient Transformer for Long Sequence Time-Series Forecasting](https://mlsanity.com/paper/2012.07436/) (2020)
- [A Time Series is Worth 64 Words: Long-term Forecasting with Transformers](https://mlsanity.com/paper/2211.14730/) (2022)
- [Autoformer: Decomposition Transformers with Auto-Correlation for Long-Term Series Forecasting](https://mlsanity.com/paper/2106.13008/) (2021)
- [Reformer: The Efficient Transformer](https://mlsanity.com/paper/2001.04451/) (2020)
- [FEDformer: Frequency Enhanced Decomposed Transformer for Long-term Series Forecasting](https://mlsanity.com/paper/2201.12740/) (2022)
- [Model Cards for Model Reporting](https://mlsanity.com/paper/1810.03993/) (2018)
- [Large Language Models Are Human-Level Prompt Engineers](https://mlsanity.com/paper/2211.01910/) (2022)
- [iTransformer: Inverted Transformers Are Effective for Time Series Forecasting](https://mlsanity.com/paper/2310.06625/) (2023)
- [Time-LLM: Time Series Forecasting by Reprogramming Large Language Models](https://mlsanity.com/paper/2310.01728/) (2023)
- [A decoder-only foundation model for time-series forecasting](https://mlsanity.com/paper/2310.10688/) (2023)
- [One Fits All:Power General Time Series Analysis by Pretrained LM](https://mlsanity.com/paper/2302.11939/) (2023)
- [Prompt Programming for Large Language Models: Beyond the Few-Shot Paradigm](https://mlsanity.com/paper/2102.07350/) (2021)
- [MOMENT: A Family of Open Time-series Foundation Models](https://mlsanity.com/paper/2402.03885/) (2024)
- [Time Series Forecasting With Deep Learning: A Survey](https://mlsanity.com/paper/2004.13408/) (2020)
- [A Transformer-based Framework for Multivariate Time Series Representation Learning](https://mlsanity.com/paper/2010.02803/) (2020)
- [Non-stationary Transformers: Exploring the Stationarity in Time Series Forecasting](https://mlsanity.com/paper/2205.14415/) (2022)
- [Foundation Models for Time Series Analysis: A Tutorial and Survey](https://mlsanity.com/paper/2403.14735/) (2024)
- [Knowledge Editing for Large Language Models: A Survey](https://mlsanity.com/paper/2310.16218/) (2023)
- [MINIROCKET: A Very Fast (Almost) Deterministic Transform for Time Series Classification](https://mlsanity.com/paper/2012.08791/) (2020)
- [TEMPO: Prompt-based Generative Pre-trained Transformer for Time Series Forecasting](https://mlsanity.com/paper/2310.04948/) (2023)
- [TEST: Text Prototype Aligned Embedding to Activate LLM's Ability for Time Series](https://mlsanity.com/paper/2308.08241/) (2023)
- [Are Language Models Actually Useful for Time Series Forecasting?](https://mlsanity.com/paper/2406.16964/) (2024)
- [UniTime: A Language-Empowered Unified Model for Cross-Domain Time Series Forecasting](https://mlsanity.com/paper/2310.09751/) (2023)
- [Self-Attention Attribution: Interpreting Information Interactions Inside Transformer](https://mlsanity.com/paper/2004.11207/) (2020)
- [UniTS: A Unified Multi-Task Time Series Model](https://mlsanity.com/paper/2403.00131/) (2024)
- [Contrast Everything: A Hierarchical Contrastive Framework for Medical Time-Series](https://mlsanity.com/paper/2310.14017/) (2023)

## Built on by (most cited first, 6 of 6)

- [MIRA: Medical Time Series Foundation Model for Real-World Health Data](https://mlsanity.com/paper/2506.07584/) (2025)
- [Cross-Subject Generalization for EEG Decoding: A Survey of Deep Learning Methods](https://mlsanity.com/paper/2604.27033/) (2026)
- [Post-Training in Time Series Foundation Models: A Unifying Framework](https://mlsanity.com/paper/2607.20002/) (2026)
- [Generating Realistic Multi-Beat ECG Signals](https://mlsanity.com/paper/2505.18189/) (2025)
- [FemWear: A Parameter-Efficient Wearable Foundation Model for Women's Health](https://mlsanity.com/paper/2608.08244/) (2026)
- [CORD: Learning Reusable Degradation Representations Across Heterogeneous Physical Systems](https://mlsanity.com/paper/2609.39784/) (2026)

## Abstract (arXiv)

Medical time series (MedTS) classification suffers from poor generalizability in real-world deployment due to inter- and intra-dataset heterogeneity, such as varying numbers of channels, signal lengths, task definitions, and patient characteristics. To address this, we propose FORMED, a novel framework for repurposing a backbone foundation model, pre-trained on generic time series, to enable highly generalizable MedTS classification on unseen datasets. FORMED combines the backbone with a novel classifier comprising two components: (1) task-specific channel embeddings and label queries, dynamically sized to match any number of channels and target classes, and (2) a shared decoding attention layer, jointly trained across datasets to capture medical domain knowledge through task-agnostic feature-query interactions. After repurposing, FORMED achieves seamless adaptation to unseen MedTS datasets through lightweight label query training (0.1% of parameters), eliminating the need for full fine-tuning or architectural redesign. We evaluate FORMED on 5 diverse MedTS datasets, benchmarking against 11 Task-Specific Models (TSM) and 4 Task-Specific Adaptation (TSA) methods. Our results demonstrate FORMED's dominant performance, achieving up to 35% absolute improvement in F1-score (on ADFTD dataset) over specialized baselines. Further analysis reveals consistent generalization across varying channel configurations, time series lengths, and clinical tasks, which are key challenges in real-world deployment. By decoupling domain-invariant representation learning from task-specific adaptation, FORMED establishes a scalable and resource-efficient paradigm for foundation model repurposing in healthcare. This approach prioritizes clinical adaptability over rigid task-centric design, offering a practical pathway for real-world implementation.
