# A Two-Stage Proactive Dialogue Generator for Efficient Clinical Information Collection Using Large Language Model

arXiv: https://arxiv.org/abs/2410.03770 · HTML: https://mlsanity.com/paper/2410.03770/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 34 references that are in the map.
- First posted on arXiv 2 Oct 2024.

## Builds on (most cited first, 15 of 15)

- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Tree of Thoughts: Deliberate Problem Solving with Large Language Models](https://mlsanity.com/paper/2305.10601/) (2023)
- [Training Compute-Optimal Large Language Models](https://mlsanity.com/paper/2203.15556/) (2022)
- [MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Models](https://mlsanity.com/paper/2304.10592/) (2023)
- [GLM: General Language Model Pretraining with Autoregressive Blank Infilling](https://mlsanity.com/paper/2103.10360/) (2021)
- [GLM-130B: An Open Bilingual Pre-trained Model](https://mlsanity.com/paper/2210.02414/) (2022)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [HuatuoGPT, towards Taming Language Model to Be a Doctor](https://mlsanity.com/paper/2305.15075/) (2023)
- [Cross-modal Memory Networks for Radiology Report Generation](https://mlsanity.com/paper/2204.13258/) (2022)
- [Biomedical Question Answering: A Survey of Approaches and Challenges](https://mlsanity.com/paper/2102.05281/) (2021)
- [ChatCAD+: Towards a Universal and Reliable Interactive CAD using LLMs](https://mlsanity.com/paper/2305.15964/) (2023)

## Built on by (most cited first, 2 of 2)

- [A Query-Aware Multi-Path Knowledge Graph Fusion Approach for Enhancing Retrieval-Augmented Generation in Large Language Models](https://mlsanity.com/paper/2507.16826/) (2025)
- [Towards Proactive Detection of User-Side Implicit Conflicts in Human-LLM Dialogue](https://mlsanity.com/paper/2609.19155/) (2026)

## Abstract (arXiv)

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and other related information that goes beyond medical evidence data (test results) to enhance disease diagnosis. However, this procedure is usually time-consuming and less-efficient, which can be potentially optimized through computer-assisted systems. As such, we propose a diagnostic dialogue system to automate the patient information collection procedure. By exploiting medical history and conversation logic, our conversation agents, particularly the doctor agent, can pose multi-round clinical queries to effectively collect the most relevant disease diagnostic information. Moreover, benefiting from our two-stage recommendation structure, carefully designed ranking criteria, and interactive patient agent, our model is able to overcome the under-exploration and non-flexible challenges in dialogue generation. Our experimental results on a real-world medical conversation dataset show that our model can generate clinical queries that mimic the conversation style of real doctors, with efficient fluency, professionalism, and safety, while effectively collecting relevant disease diagnostic information.