# From Epilepsy Seizures Classification to Detection: A Deep Learning-based Approach for Raw EEG Signals

arXiv: https://arxiv.org/abs/2410.03385 · HTML: https://mlsanity.com/paper/2410.03385/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 56 references that are in the map.
- First posted on arXiv 4 Oct 2024.

## Builds on (most cited first, 11 of 11)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [RoFormer: Enhanced Transformer with Rotary Position Embedding](https://mlsanity.com/paper/2104.09864/) (2021)
- [Learning Phrase Representations using RNN Encoder-Decoder for Statistical Machine Translation](https://mlsanity.com/paper/1406.1078/) (2014)
- [Long Short-Term Memory Based Recurrent Neural Network Architectures for Large Vocabulary Speech Recognition](https://mlsanity.com/paper/1402.1128/) (2014)
- [U-Time: A Fully Convolutional Network for Time Series Segmentation Applied to Sleep Staging](https://mlsanity.com/paper/1910.11162/) (2019)
- [Deep Learning in Bioinformatics](https://mlsanity.com/paper/1603.06430/) (2016)
- [Machine Learning for Predicting Epileptic Seizures Using EEG Signals: A Review](https://mlsanity.com/paper/2002.01925/) (2020)
- [Interpretable Deep Neural Networks for Single-Trial EEG Classification](https://mlsanity.com/paper/1604.08201/) (2016)
- [Automatic Diagnosis of Schizophrenia in EEG Signals Using CNN-LSTM Models](https://mlsanity.com/paper/2109.01120/) (2021)
- [Automated Detection of Abnormalities from an EEG Recording of Epilepsy Patients With a Compact Convolutional Neural Network](https://mlsanity.com/paper/2105.10358/) (2021)

## Abstract (arXiv)

Epilepsy represents the most prevalent neurological disease in the world. One-third of people suffering from mesial temporal lobe epilepsy (MTLE) exhibit drug resistance, urging the need to develop new treatments. A key part in anti-seizure medication (ASM) development is the capability of detecting and quantifying epileptic seizures occurring in electroencephalogram (EEG) signals, which is crucial for treatment efficacy evaluation. In this study, we introduced a seizure detection pipeline based on deep learning models applied to raw EEG signals. This pipeline integrates: a new pre-processing technique which segments continuous raw EEG signals without prior distinction between seizure and seizure-free activities; a post-processing algorithm developed to reassemble EEG segments and allow the identification of seizures start/end; and finally, a new evaluation procedure based on a strict seizure events comparison between predicted and real labels. Models training have been performed using a data splitting strategy which addresses the potential for data leakage. We demonstrated the fundamental differences between a seizure classification and a seizure detection task and showed the differences in performance between the two tasks. Finally, we demonstrated the generalization capabilities across species of our best architecture, combining a Convolutional Neural Network and a Transformer encoder. The model was trained on animal EEGs and tested on human EEGs with a F1-score of 93% on a balanced Bonn dataset.