# Lost in Tracking: Uncertainty-guided Cardiac Cine MRI Segmentation at Right Ventricle Base

arXiv: https://arxiv.org/abs/2410.03320 · HTML: https://mlsanity.com/paper/2410.03320/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 29 references that are in the map.
- First posted on arXiv 4 Oct 2024.

## Builds on (most cited first, 13 of 13)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [Simple and Scalable Predictive Uncertainty Estimation using Deep Ensembles](https://mlsanity.com/paper/1612.01474/) (2016)
- [What Uncertainties Do We Need in Bayesian Deep Learning for Computer Vision?](https://mlsanity.com/paper/1703.04977/) (2017)
- [VoxelMorph: A Learning Framework for Deformable Medical Image Registration](https://mlsanity.com/paper/1809.05231/) (2018)
- [Stochastic Gradient Hamiltonian Monte Carlo](https://mlsanity.com/paper/1402.4102/) (2014)
- [Semantic Video Segmentation by Gated Recurrent Flow Propagation](https://mlsanity.com/paper/1612.08871/) (2016)
- [Joint Learning of Motion Estimation and Segmentation for Cardiac MR Image Sequences](https://mlsanity.com/paper/1806.04066/) (2018)
- [Recurrent neural networks for aortic image sequence segmentation with sparse annotations](https://mlsanity.com/paper/1808.00273/) (2018)
- [Efficient Bayesian Uncertainty Estimation for nnU-Net](https://mlsanity.com/paper/2212.06278/) (2022)
- [Left Ventricle Segmentation via Optical-Flow-Net from Short-axis Cine MRI: Preserving the Temporal Coherence of Cardiac Motion](https://mlsanity.com/paper/1810.08753/) (2018)
- [DeU-Net: Deformable U-Net for 3D Cardiac MRI Video Segmentation](https://mlsanity.com/paper/2007.06341/) (2020)
- [Bayesian Uncertainty Estimation by Hamiltonian Monte Carlo: Applications to Cardiac MRI Segmentation](https://mlsanity.com/paper/2403.02311/) (2024)

## Built on by (most cited first, 1 of 1)

- [Uncertainty Quantification for Machine Learning in Healthcare: A Survey](https://mlsanity.com/paper/2505.02874/) (2025)

## Abstract (arXiv)

Accurate biventricular segmentation of cardiac magnetic resonance (CMR) cine images is essential for the clinical evaluation of heart function. However, compared to left ventricle (LV), right ventricle (RV) segmentation is still more challenging and less reproducible. Degenerate performance frequently occurs at the RV base, where the in-plane anatomical structures are complex (with atria, valve, and aorta) and vary due to the strong interplanar motion. In this work, we propose to address the currently unsolved issues in CMR segmentation, specifically at the RV base, with two strategies: first, we complemented the public resource by reannotating the RV base in the ACDC dataset, with refined delineation of the right ventricle outflow tract (RVOT), under the guidance of an expert cardiologist. Second, we proposed a novel dual encoder U-Net architecture that leverages temporal incoherence to inform the segmentation when interplanar motions occur. The inter-planar motion is characterized by loss-of-tracking, via Bayesian uncertainty of a motion-tracking model. Our experiments showed that our method significantly improved RV base segmentation taking into account temporal incoherence. Furthermore, we investigated the reproducibility of deep learning-based segmentation and showed that the combination of consistent annotation and loss of tracking could enhance the reproducibility of RV segmentation, potentially facilitating a large number of clinical studies focusing on RV.
