# Coordinate-Based Neural Representation Enabling Zero-Shot Learning for 3D Multiparametric Quantitative MRI

arXiv: https://arxiv.org/abs/2410.01577 · HTML: https://mlsanity.com/paper/2410.01577/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 41 references that are in the map.
- First posted on arXiv 2 Oct 2024.

## Builds on (most cited first, 9 of 9)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Instant Neural Graphics Primitives with a Multiresolution Hash Encoding](https://mlsanity.com/paper/2201.05989/) (2022)
- [Implicit Neural Representations with Periodic Activation Functions](https://mlsanity.com/paper/2006.09661/) (2020)
- [Fourier Features Let Networks Learn High Frequency Functions in Low Dimensional Domains](https://mlsanity.com/paper/2006.10739/) (2020)
- [Learned Initializations for Optimizing Coordinate-Based Neural Representations](https://mlsanity.com/paper/2012.02189/) (2020)
- [NeRP: Implicit Neural Representation Learning with Prior Embedding for Sparsely Sampled Image Reconstruction](https://mlsanity.com/paper/2108.10991/) (2021)
- [An Arbitrary Scale Super-Resolution Approach for 3D MR Images via Implicit Neural Representation](https://mlsanity.com/paper/2110.14476/) (2021)
- [Self-Supervised Coordinate Projection Network for Sparse-View Computed Tomography](https://mlsanity.com/paper/2209.05483/) (2022)
- [IMJENSE: Scan-specific Implicit Representation for Joint Coil Sensitivity and Image Estimation in Parallel MRI](https://mlsanity.com/paper/2311.12892/) (2023)

## Abstract (arXiv)

Quantitative magnetic resonance imaging (qMRI) offers tissue-specific physical parameters with significant potential for neuroscience research and clinical practice. However, lengthy scan times for 3D multiparametric qMRI acquisition limit its clinical utility. Here, we propose SUMMIT, an innovative imaging methodology that includes data acquisition and an unsupervised reconstruction for simultaneous multiparametric qMRI. SUMMIT first encodes multiple important quantitative properties into highly undersampled k-space. It further leverages implicit neural representation incorporated with a dedicated physics model to reconstruct the desired multiparametric maps without needing external training datasets. SUMMIT delivers co-registered T1, T2, T2*, and quantitative susceptibility mapping. Extensive simulations and phantom imaging demonstrate SUMMIT's high accuracy. Additionally, the proposed unsupervised approach for qMRI reconstruction also introduces a novel zero-shot learning paradigm for multiparametric imaging applicable to various medical imaging modalities.