# See Detail Say Clear: Towards Brain CT Report Generation via Pathological Clue-driven Representation Learning

arXiv: https://arxiv.org/abs/2409.19676 · HTML: https://mlsanity.com/paper/2409.19676/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 31 of its 49 references that are in the map.
- First posted on arXiv 29 Sep 2024.

## Builds on (most cited first, 30 of 31)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Representation Learning with Contrastive Predictive Coding](https://mlsanity.com/paper/1807.03748/) (2018)
- [CIDEr: Consensus-based Image Description Evaluation](https://mlsanity.com/paper/1411.5726/) (2014)
- [Show, Attend and Tell: Neural Image Caption Generation with Visual Attention](https://mlsanity.com/paper/1502.03044/) (2015)
- [SciBERT: A Pretrained Language Model for Scientific Text](https://mlsanity.com/paper/1903.10676/) (2019)
- [Bottom-Up and Top-Down Attention for Image Captioning and Visual Question Answering](https://mlsanity.com/paper/1707.07998/) (2017)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Show and Tell: A Neural Image Caption Generator](https://mlsanity.com/paper/1411.4555/) (2014)
- [Language Model Beats Diffusion -- Tokenizer is Key to Visual Generation](https://mlsanity.com/paper/2310.05737/) (2023)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [The Platonic Representation Hypothesis](https://mlsanity.com/paper/2405.07987/) (2024)
- [On the Automatic Generation of Medical Imaging Reports](https://mlsanity.com/paper/1711.08195/) (2017)
- [Cross-modal Memory Networks for Radiology Report Generation](https://mlsanity.com/paper/2204.13258/) (2022)
- [When Radiology Report Generation Meets Knowledge Graph](https://mlsanity.com/paper/2002.08277/) (2020)
- [Hybrid Retrieval-Generation Reinforced Agent for Medical Image Report Generation](https://mlsanity.com/paper/1805.08298/) (2018)
- [TieNet: Text-Image Embedding Network for Common Thorax Disease Classification and Reporting in Chest X-rays](https://mlsanity.com/paper/1801.04334/) (2018)
- [Dynamic Graph Enhanced Contrastive Learning for Chest X-ray Report Generation](https://mlsanity.com/paper/2303.10323/) (2023)
- [A Hierarchical Approach for Generating Descriptive Image Paragraphs](https://mlsanity.com/paper/1611.06607/) (2016)
- [Knowledge-driven Encode, Retrieve, Paraphrase for Medical Image Report Generation](https://mlsanity.com/paper/1903.10122/) (2019)
- [PromptMRG: Diagnosis-Driven Prompts for Medical Report Generation](https://mlsanity.com/paper/2308.12604/) (2023)
- [Competence-based Multimodal Curriculum Learning for Medical Report Generation](https://mlsanity.com/paper/2206.14579/) (2022)
- [Contrastive Attention for Automatic Chest X-ray Report Generation](https://mlsanity.com/paper/2106.06965/) (2021)
- [Knowledge Matters: Radiology Report Generation with General and Specific Knowledge](https://mlsanity.com/paper/2112.15009/) (2021)
- [AlignTransformer: Hierarchical Alignment of Visual Regions and Disease Tags for Medical Report Generation](https://mlsanity.com/paper/2203.10095/) (2022)
- [Show, Describe and Conclude: On Exploiting the Structure Information of Chest X-Ray Reports](https://mlsanity.com/paper/2004.12274/) (2020)
- [Weakly Supervised Contrastive Learning for Chest X-Ray Report Generation](https://mlsanity.com/paper/2109.12242/) (2021)
- [Dia-LLaMA: Towards Large Language Model-driven CT Report Generation](https://mlsanity.com/paper/2403.16386/) (2024)

## Built on by (most cited first, 2 of 2)

- [Multimodal Large Language Models for Medicine: A Comprehensive Survey](https://mlsanity.com/paper/2504.21051/) (2025)
- [MEPNet: Medical Entity-balanced Prompting Network for Brain CT Report Generation](https://mlsanity.com/paper/2503.17784/) (2025)

## Abstract (arXiv)

Brain CT report generation is significant to aid physicians in diagnosing cranial diseases. Recent studies concentrate on handling the consistency between visual and textual pathological features to improve the coherence of report. However, there exist some challenges: 1) Redundant visual representing: Massive irrelevant areas in 3D scans distract models from representing salient visual contexts. 2) Shifted semantic representing: Limited medical corpus causes difficulties for models to transfer the learned textual representations to generative layers. This study introduces a Pathological Clue-driven Representation Learning (PCRL) model to build cross-modal representations based on pathological clues and naturally adapt them for accurate report generation. Specifically, we construct pathological clues from perspectives of segmented regions, pathological entities, and report themes, to fully grasp visual pathological patterns and learn cross-modal feature representations. To adapt the representations for the text generation task, we bridge the gap between representation learning and report generation by using a unified large language model (LLM) with task-tailored instructions. These crafted instructions enable the LLM to be flexibly fine-tuned across tasks and smoothly transfer the semantic representation for report generation. Experiments demonstrate that our method outperforms previous methods and achieves SoTA performance. Our code is available at "https://github.com/Chauncey-Jheng/PCRL-MRG".