# Investigating Gender Bias in Lymph-node Segmentation with Anatomical Priors

arXiv: https://arxiv.org/abs/2409.15888 · HTML: https://mlsanity.com/paper/2409.15888/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 5 of its 20 references that are in the map.
- First posted on arXiv 24 Sep 2024.

## Builds on (most cited first, 5 of 5)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentation](https://mlsanity.com/paper/1809.10486/) (2018)
- [Fairness in Cardiac MR Image Analysis: An Investigation of Bias Due to Data Imbalance in Deep Learning Based Segmentation](https://mlsanity.com/paper/2106.12387/) (2021)
- [An investigation into the impact of deep learning model choice on sex and race bias in cardiac MR segmentation](https://mlsanity.com/paper/2308.13415/) (2023)

## Built on by (most cited first, 1 of 1)

- [Efficient KernelSHAP Explanations for Patch-based 3D Medical Image Segmentation](https://mlsanity.com/paper/2604.11775/) (2026)

## Abstract (arXiv)

Radiotherapy requires precise segmentation of organs at risk (OARs) and of the Clinical Target Volume (CTV) to maximize treatment efficacy and minimize toxicity. While deep learning (DL) has significantly advanced automatic contouring, complex targets like CTVs remain challenging. This study explores the use of simpler, well-segmented structures (e.g., OARs) as Anatomical Prior (AP) information to improve CTV segmentation. We investigate gender bias in segmentation models and the mitigation effect of the prior information. Findings indicate that incorporating prior knowledge with the discussed strategies enhances segmentation quality in female patients and reduces gender bias, particularly in the abdomen region. This research provides a comparative analysis of new encoding strategies and highlights the potential of using AP to achieve fairer segmentation outcomes.