# ViKL: A Mammography Interpretation Framework via Multimodal Aggregation of Visual-knowledge-linguistic Features

arXiv: https://arxiv.org/abs/2409.15744 · HTML: https://mlsanity.com/paper/2409.15744/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 40 of its 62 references that are in the map.
- First posted on arXiv 24 Sep 2024.

## Builds on (most cited first, 30 of 40)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Momentum Contrast for Unsupervised Visual Representation Learning](https://mlsanity.com/paper/1911.05722/) (2019)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [BLIP: Bootstrapping Language-Image Pre-training for Unified Vision-Language Understanding and Generation](https://mlsanity.com/paper/2201.12086/) (2022)
- [Learning Deep Features for Discriminative Localization](https://mlsanity.com/paper/1512.04150/) (2015)
- [BEiT: BERT Pre-Training of Image Transformers](https://mlsanity.com/paper/2106.08254/) (2021)
- [RandAugment: Practical automated data augmentation with a reduced search space](https://mlsanity.com/paper/1909.13719/) (2019)
- [Align before Fuse: Vision and Language Representation Learning with Momentum Distillation](https://mlsanity.com/paper/2107.07651/) (2021)
- [Unsupervised Representation Learning by Predicting Image Rotations](https://mlsanity.com/paper/1803.07728/) (2018)
- [Understanding Contrastive Representation Learning through Alignment and Uniformity on the Hypersphere](https://mlsanity.com/paper/2005.10242/) (2020)
- [Unsupervised Learning of Visual Representations by Solving Jigsaw Puzzles](https://mlsanity.com/paper/1603.09246/) (2016)
- [Contrastive Multiview Coding](https://mlsanity.com/paper/1906.05849/) (2019)
- [CoCa: Contrastive Captioners are Image-Text Foundation Models](https://mlsanity.com/paper/2205.01917/) (2022)
- [ViLT: Vision-and-Language Transformer Without Convolution or Region Supervision](https://mlsanity.com/paper/2102.03334/) (2021)
- [When Does Label Smoothing Help?](https://mlsanity.com/paper/1906.02629/) (2019)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [PaLI: A Jointly-Scaled Multilingual Language-Image Model](https://mlsanity.com/paper/2209.06794/) (2022)
- [Contrastive Learning with Hard Negative Samples](https://mlsanity.com/paper/2010.04592/) (2020)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [VLMo: Unified Vision-Language Pre-Training with Mixture-of-Modality-Experts](https://mlsanity.com/paper/2111.02358/) (2021)
- [Vision-Language Pre-Training with Triple Contrastive Learning](https://mlsanity.com/paper/2202.10401/) (2022)
- [Models Genesis: Generic Autodidactic Models for 3D Medical Image Analysis](https://mlsanity.com/paper/1908.06912/) (2019)
- [MedKLIP: Medical Knowledge Enhanced Language-Image Pre-Training in Radiology](https://mlsanity.com/paper/2301.02228/) (2023)

## Abstract (arXiv)

Mammography is the primary imaging tool for breast cancer diagnosis. Despite significant strides in applying deep learning to interpret mammography images, efforts that focus predominantly on visual features often struggle with generalization across datasets. We hypothesize that integrating additional modalities in the radiology practice, notably the linguistic features of reports and manifestation features embodying radiological insights, offers a more powerful, interpretable and generalizable representation. In this paper, we announce MVKL, the first multimodal mammography dataset encompassing multi-view images, detailed manifestations and reports. Based on this dataset, we focus on the challanging task of unsupervised pretraining and propose ViKL, a innovative framework that synergizes Visual, Knowledge, and Linguistic features. This framework relies solely on pairing information without the necessity for pathology labels, which are often challanging to acquire. ViKL employs a triple contrastive learning approach to merge linguistic and knowledge-based insights with visual data, enabling both inter-modality and intra-modality feature enhancement. Our research yields significant findings: 1) Integrating reports and manifestations with unsupervised visual pretraining, ViKL substantially enhances the pathological classification and fosters multimodal interactions. 2) Manifestations can introduce a novel hard negative sample selection mechanism. 3) The multimodal features demonstrate transferability across different datasets. 4) The multimodal pretraining approach curbs miscalibrations and crafts a high-quality representation space. The MVKL dataset and ViKL code are publicly available at https://github.com/wxwxwwxxx/ViKL to support a broad spectrum of future research.