# I2I-Galip: Unsupervised Medical Image Translation Using Generative Adversarial CLIP

arXiv: https://arxiv.org/abs/2409.12399 · HTML: https://mlsanity.com/paper/2409.12399/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 36 references that are in the map.
- First posted on arXiv 19 Sep 2024.

## Builds on (most cited first, 29 of 29)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [Prompt-to-Prompt Image Editing with Cross Attention Control](https://mlsanity.com/paper/2208.01626/) (2022)
- [StarGAN v2: Diverse Image Synthesis for Multiple Domains](https://mlsanity.com/paper/1912.01865/) (2019)
- [StarGAN: Unified Generative Adversarial Networks for Multi-Domain Image-to-Image Translation](https://mlsanity.com/paper/1711.09020/) (2017)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [Least Squares Generative Adversarial Networks](https://mlsanity.com/paper/1611.04076/) (2016)
- [Plug-and-Play Diffusion Features for Text-Driven Image-to-Image Translation](https://mlsanity.com/paper/2211.12572/) (2022)
- [Multimodal Unsupervised Image-to-Image Translation](https://mlsanity.com/paper/1804.04732/) (2018)
- [Unsupervised Image-to-Image Translation Networks](https://mlsanity.com/paper/1703.00848/) (2017)
- [Diverse Image-to-Image Translation via Disentangled Representations](https://mlsanity.com/paper/1808.00948/) (2018)
- [StyleGAN-T: Unlocking the Power of GANs for Fast Large-Scale Text-to-Image Synthesis](https://mlsanity.com/paper/2301.09515/) (2023)
- [Splicing ViT Features for Semantic Appearance Transfer](https://mlsanity.com/paper/2201.00424/) (2022)
- [Unsupervised Medical Image Translation with Adversarial Diffusion Models](https://mlsanity.com/paper/2207.08208/) (2022)
- [U-GAT-IT: Unsupervised Generative Attentional Networks with Adaptive Layer-Instance Normalization for Image-to-Image Translation](https://mlsanity.com/paper/1907.10830/) (2019)
- [EGSDE: Unpaired Image-to-Image Translation via Energy-Guided Stochastic Differential Equations](https://mlsanity.com/paper/2207.06635/) (2022)
- [MedGAN: Medical Image Translation using GANs](https://mlsanity.com/paper/1806.06397/) (2018)
- [Diffusion-based Image Translation using Disentangled Style and Content Representation](https://mlsanity.com/paper/2209.15264/) (2022)
- [Image Synthesis in Multi-Contrast MRI with Conditional Generative Adversarial Networks](https://mlsanity.com/paper/1802.01221/) (2018)
- [One-Step Image Translation with Text-to-Image Models](https://mlsanity.com/paper/2403.12036/) (2024)
- [GALIP: Generative Adversarial CLIPs for Text-to-Image Synthesis](https://mlsanity.com/paper/2301.12959/) (2023)
- [Dual Contrastive Learning for Unsupervised Image-to-Image Translation](https://mlsanity.com/paper/2104.07689/) (2021)
- [CoLa-Diff: Conditional Latent Diffusion Model for Multi-Modal MRI Synthesis](https://mlsanity.com/paper/2303.14081/) (2023)
- [UVCGAN: UNet Vision Transformer cycle-consistent GAN for unpaired image-to-image translation](https://mlsanity.com/paper/2203.02557/) (2022)
- [MedM2G: Unifying Medical Multi-Modal Generation via Cross-Guided Diffusion with Visual Invariant](https://mlsanity.com/paper/2403.04290/) (2024)
- [In2I : Unsupervised Multi-Image-to-Image Translation Using Generative Adversarial Networks](https://mlsanity.com/paper/1711.09334/) (2017)
- [LANIT: Language-Driven Image-to-Image Translation for Unlabeled Data](https://mlsanity.com/paper/2208.14889/) (2022)

## Built on by (most cited first, 2 of 2)

- [Structure-Accurate Medical Image Translation via Dynamic Frequency Balance and Knowledge Guidance](https://mlsanity.com/paper/2504.09441/) (2025)
- [Next-Acceleration-Scale Prediction for Autoregressive MRI Reconstruction](https://mlsanity.com/paper/2605.19354/) (2026)

## Abstract (arXiv)

Unpaired image-to-image translation is a challenging task due to the absence of paired examples, which complicates learning the complex mappings between the distinct distributions of the source and target domains. One of the most commonly used approach for this task is CycleGAN which requires the training of a new pair of generator-discriminator networks for each domain pair. In this paper, we propose a new image-to-image translation framework named Image-to-Image-Generative-Adversarial-CLIP (I2I-Galip) where we utilize a pre-trained multi-model foundation model (i.e., CLIP) to mitigate the need of separate generator-discriminator pairs for each source-target mapping while achieving better and more efficient multi-domain translation. By utilizing the massive knowledge gathered during pre-training a foundation model, our approach makes use of a single lightweight generator network with ~13M parameters for the multi-domain image translation task. Comprehensive experiments on translation performance in public MRI and CT datasets show the superior performance of the proposed framework over the existing approaches. Code will be available (https://github.com/yilmazkorkmaz1/I2I-Galip).