# DX2CT: Diffusion Model for 3D CT Reconstruction from Bi or Mono-planar 2D X-ray(s)

arXiv: https://arxiv.org/abs/2409.08850 · HTML: https://mlsanity.com/paper/2409.08850/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 21 of its 35 references that are in the map.
- First posted on arXiv 13 Sep 2024.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 21 of 21)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Scalable Diffusion Models with Transformers](https://mlsanity.com/paper/2212.09748/) (2022)
- [Pyramid Vision Transformer: A Versatile Backbone for Dense Prediction without Convolutions](https://mlsanity.com/paper/2102.12122/) (2021)
- [Image Super-Resolution via Iterative Refinement](https://mlsanity.com/paper/2104.07636/) (2021)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Semantic Image Synthesis with Spatially-Adaptive Normalization](https://mlsanity.com/paper/1903.07291/) (2019)
- [Denoising Diffusion Restoration Models](https://mlsanity.com/paper/2201.11793/) (2022)
- [PadChest: A large chest x-ray image dataset with multi-label annotated reports](https://mlsanity.com/paper/1901.07441/) (2019)
- [Semantic Image Synthesis via Diffusion Models](https://mlsanity.com/paper/2207.00050/) (2022)
- [X2CT-GAN: Reconstructing CT from Biplanar X-Rays with Generative Adversarial Networks](https://mlsanity.com/paper/1905.06902/) (2019)
- [Perspective Projection-Based 3D CT Reconstruction from Biplanar X-rays](https://mlsanity.com/paper/2303.05297/) (2023)
- [DIFR3CT: Latent Diffusion for Probabilistic 3D CT Reconstruction from Few Planar X-Rays](https://mlsanity.com/paper/2408.15118/) (2024)
- [XctDiff: Reconstruction of CT Images with Consistent Anatomical Structures from a Single Radiographic Projection Image](https://mlsanity.com/paper/2406.04679/) (2024)

## Built on by (most cited first, 8 of 8)

- [SV-DRR: High-Fidelity Novel View X-Ray Synthesis Using Diffusion Model](https://mlsanity.com/paper/2507.05148/) (2025)
- [MoTDiff: High-resolution Motion Trajectory estimation from a single blurred image using Diffusion models](https://mlsanity.com/paper/2510.26173/) (2025)
- [XDen-1K: A Density Field Dataset of Real-World Objects](https://mlsanity.com/paper/2512.10668/) (2025)
- [DuFal: Dual-Frequency-Aware Learning for High-Fidelity Extremely Sparse-view CBCT Reconstruction](https://mlsanity.com/paper/2601.15416/) (2026)
- [Conditional Diffusion for 3D CT Volume Reconstruction from 2D X-rays](https://mlsanity.com/paper/2603.26509/) (2026)
- [From Sparse X-rays to 3D CT: Training-Free Reconstruction with Diffusion Priors](https://mlsanity.com/paper/2606.20763/) (2026)
- [Learning Where and What to Lift for Bi-planar X-ray-to-CT Reconstruction](https://mlsanity.com/paper/2608.17255/) (2026)
- [VS-Splat: Voxel-Selective feed-forward Gaussian Splatting for end-to-end 3D object reconstruction from sparse-views](https://mlsanity.com/paper/2609.12343/) (2026)

## Abstract (arXiv)

Computational tomography (CT) provides high-resolution medical imaging, but it can expose patients to high radiation. X-ray scanners have low radiation exposure, but their resolutions are low. This paper proposes a new conditional diffusion model, DX2CT, that reconstructs three-dimensional (3D) CT volumes from bi or mono-planar X-ray image(s). Proposed DX2CT consists of two key components: 1) modulating feature maps extracted from two-dimensional (2D) X-ray(s) with 3D positions of CT volume using a new transformer and 2) effectively using the modulated 3D position-aware feature maps as conditions of DX2CT. In particular, the proposed transformer can provide conditions with rich information of a target CT slice to the conditional diffusion model, enabling high-quality CT reconstruction. Our experiments with the bi or mono-planar X-ray(s) benchmark datasets show that proposed DX2CT outperforms several state-of-the-art methods. Our codes and model will be available at: https://www.github.com/intyeger/DX2CT.