# Eir: Thai Medical Large Language Models

arXiv: https://arxiv.org/abs/2409.08523 · HTML: https://mlsanity.com/paper/2409.08523/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 24 of its 31 references that are in the map.
- First posted on arXiv 13 Sep 2024.

## Builds on (most cited first, 24 of 24)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [SciBERT: A Pretrained Language Model for Scientific Text](https://mlsanity.com/paper/1903.10676/) (2019)
- [ZeRO: Memory Optimizations Toward Training Trillion Parameter Models](https://mlsanity.com/paper/1910.02054/) (2019)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [Large Language Models](https://mlsanity.com/paper/2307.05782/) (2023)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [What Makes Good Data for Alignment? A Comprehensive Study of Automatic Data Selection in Instruction Tuning](https://mlsanity.com/paper/2312.15685/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [A Rank Stabilization Scaling Factor for Fine-Tuning with LoRA](https://mlsanity.com/paper/2312.03732/) (2023)
- [Agent Hospital: A Simulacrum of Hospital with Evolvable Medical Agents](https://mlsanity.com/paper/2405.02957/) (2024)
- [Arcee's MergeKit: A Toolkit for Merging Large Language Models](https://mlsanity.com/paper/2403.13257/) (2024)
- [A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethics](https://mlsanity.com/paper/2310.05694/) (2023)
- [Benchmarking large language models for biomedical natural language processing applications and recommendations](https://mlsanity.com/paper/2305.16326/) (2023)
- [Publicly Shareable Clinical Large Language Model Built on Synthetic Clinical Notes](https://mlsanity.com/paper/2309.00237/) (2023)
- [DARE: Data Augmented Relation Extraction with GPT-2](https://mlsanity.com/paper/2004.13845/) (2020)
- [SEACrowd: A Multilingual Multimodal Data Hub and Benchmark Suite for Southeast Asian Languages](https://mlsanity.com/paper/2406.10118/) (2024)
- [Typhoon: Thai Large Language Models](https://mlsanity.com/paper/2312.13951/) (2023)
- [Health-LLM: Personalized Retrieval-Augmented Disease Prediction System](https://mlsanity.com/paper/2402.00746/) (2024)
- [A PubMedBERT-based Classifier with Data Augmentation Strategy for Detecting Medication Mentions in Tweets](https://mlsanity.com/paper/2112.02998/) (2021)

## Built on by (most cited first, 1 of 1)

- [Reasoning LLMs in the Medical Domain: A Literature Survey](https://mlsanity.com/paper/2508.19097/) (2025)

## Abstract (arXiv)

We present Eir-8B, a large language model with 8 billion parameters, specifically designed to enhance the accuracy of handling medical tasks in the Thai language. This model focuses on providing clear and easy-to-understand answers for both healthcare professionals and patients, thereby improving the efficiency of diagnosis and treatment processes. Human evaluation was conducted to ensure that the model adheres to care standards and provides unbiased answers. To prioritize data security, the model is deployed within the hospital's internal network, ensuring both high security and faster processing speeds. The internal API connection is secured with encryption and strict authentication measures to prevent data leaks and unauthorized access. We evaluated several open-source large language models with 8 billion parameters on four medical benchmarks: MedQA, MedMCQA, PubMedQA, and the medical subset of MMLU. The best-performing baselines were used to develop Eir-8B. Our evaluation employed multiple questioning strategies, including zero-shot, few-shot, chain-of-thought reasoning, and ensemble/self-consistency voting methods. Our model outperformed commercially available Thai-language large language models by more than 10%. In addition, we developed enhanced model testing tailored for clinical use in Thai across 18 clinical tasks, where our model exceeded GPT-4o performance by more than 11%.